关键词: 腰椎磁共振成像多定量序列, 临床疼痛, 功能障碍指数量表, 相关性

Abstract: Objective　To analyze the correlation of the multi-quantitative sequence of magnetic resonance imaging (MRI) with low back pain and score of Oswestry Disability Index (ODI). Methods　One hundred and twenty patients with low back pain who underwent lumbar MRI in Hubei No.3 People's Hospital of Jianghan University from April 2018 to October 2019 were randomly selected, including 54 males and 66 females, and they were 18-42 (32.18 ± 3.24) years old. According to the duration of pain, they divided into an acute low back pain group (45 cases; the pain duration ≤ 12 weeks) and a chronic low back pain group (75 cases; the pain > 12 weeks). The quantitative values of T1, T2, and PD of anterior annulus fibrosus, posterior annulus fibrosus, nucleus pulposus, and paravertebral muscles between L1/2 and L5/S1 were obtained. The Visual Analogue Scale (VAS) and ODI were used to evaluate the degree of pain and dysfunction. The statistical differences in the general data, VAS score, and ODI score between the two groups were analyzed by the independent-sample t test. Pearson correlation was used to analyze the correlation of the VAS and ODI scores with the clinical data and the T1, T2 and PD quantitative values of anterior and posterior annulus fibrosus, nucleus pulposus, and paravertebral muscles. Results　There were no statistical differences in the general data, such as gender, age, and Pfirrmann classification, between the two groups (all P>0.05). There were no statistical differences in the scores of VAS and ODI between the two groups (both P>0.05). There were statistical differences in the T1 and T2 values of nucleus pulposus, T1 value of anterior annulus fibrosus, and T2 value of psoas major muscle between the two groups (all P<0.05). Pearson correlation analysis showed that the VAS and ODI scores were positively correlated with Pfirrmann grade, the VAS score was positively correlated with the T2 value of multifidus muscle, the ODI score was positively correlated with the body mass index and T2 value of posterior annulus fibrosus and negatively correlated with the PD, T2, and T1 values of nucleus pulposus in the acute low back pain group (all P<0.05); the VAS score was positively correlated with the PD and T1 values of posterior annulus fibrosus and the ODI score was positively correlated with the T2 value of posterior annulus fibrosus in the chronic low back pain group (r=0.414, 0.219, and 0.196; all P<0.05). Conclusions　The PD, T2, and T1 values of lumbar disc and paraspinal muscles are significantly correlated with VAS and ODI scores. The values of PD, T2, and T1 play an important role in the evaluation of lumbar disc degeneration.

Key words: Lumbar magnetic resonance imaging multi-quantitative sequence, Clinical pain, Oswestry Disability Index, Correlation