关键词: 妊娠期糖尿病, 新生儿, 血糖变化, 相关因素

Abstract: Objective　To investigate the related factors of blood glucose change in newborns born to women with gestational diabetes mellitus (GDM). Methods　A total of 200 pregnant women with GDM who delivered in Taishan People's Hospital from January 2019 to April 2021 were collected. Blood glucose was detected 1 h, 3 h, 6 h, 12 h, and 24 h after birth, and the neonatal birth weight and feeding status and maternal gestational age, delivery mode, and lactation status 24 h after birth were collected. Chi-square test was used for the count data, and logistic regression was used for multivariate regression analysis. Results　The lowest blood glucose was (3.42±1.06) mmol/L 1 h after birth, the blood glucose gradually increased after birth, and the neonatal blood glucose levels 3 h, 6 h, 12 h, and 24 h after birth were (3.49±1.05), (3.58±1.14), (4.01±0.52), and (4.39±0.48) mmol/L, respectively. Among them, 46 newborns (23.0%) were still hypoglycemic 24 h after birth. Gestational age ≤38 weeks, neonatal body weight <3 000 g, and lactation 24 h after birth were the independent risk factors of hypoglycemia 24 h after birth (all P<0.05). Conclusions　Gestational age, neonatal body weight, and 24 h lactation volume are the main factors affecting hypoglycemia in newborns born to women with GDM 24 h after birth. We should pay special attention to these factors in clinical practice so as to prevent the occurrence of neonatal hypoglycemia in early stage.

Key words: Gestational diabetes mellitus, Newborns, Blood glucose change, Related factors