关键词: 结直肠癌, 歧视知觉, 身心健康, 健康相关生命质量, 干预措施, 相关性

Abstract:

Objective　To explore the current status and risk factors of discrimination perception among patients with colorectal cancer, and to analyze its correlation with health-related quality of life (HRQoL). Methods　From August 2024 to May 2025, a questionnaire survey was conducted among 420 colorectal cancer patients who visited three top-tier hospitals in the central and western regions (Nanchang First Hospital, Anning First People's Hospital, and the High-tech Hospital of the First Affiliated Hospital of Nanchang University) using the Social Data Questionnaire, the Cancer Stigma Perception Scale (CSPDS), and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30). Descriptive statistical analysis was used to assess the current status of patients' perception of discrimination. Single-factor ANOVA and multiple-factor linear regression were employed to analyze the risk factors for patients' perception of discrimination, and to explore its correlation with HRQoL. Results　There was a widespread perception of discrimination among 420 patients with colorectal cancer, with a score of 48(40,55).Multivariate linear regression analysis showed that financial hardship, history of intestinal fistula, and introverted personality were all risk factors for patients' perception of discrimination (P<0.05). The patients' perception of discrimination was negatively correlated with HRQoL, five functional domains, overall health, symptom domains, and financial hardship (P<0.05). Conclusions　The widespread perception of discrimination is detrimental to the recovery and improvement of the quality of life of patients with colorectal cancer. Early identification and proactive, effective measures to address this issue are key to reducing the perception of discrimination and can serve as a starting point for further enhancing the health-related quality of life (HRQoL) of these patients in the future.

Objective　To explore the current status and risk factors of discrimination perception among patients with colorectal cancer, and to analyze its correlation with health-related quality of life (HRQoL). Methods　From August 2024 to May 2025, a questionnaire survey was conducted among 420 colorectal cancer patients who visited three top-tier hospitals in the central and western regions (Nanchang First Hospital, Anning First People's Hospital, and the High-tech Hospital of the First Affiliated Hospital of Nanchang University) using the Social Data Questionnaire, the Cancer Stigma Perception Scale (CSPDS), and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30). Descriptive statistical analysis was used to assess the current status of patients' perception of discrimination. Single-factor ANOVA and multiple-factor linear regression were employed to analyze the risk factors for patients' perception of discrimination, and to explore its correlation with HRQoL. Results　There was a widespread perception of discrimination among 420 patients with colorectal cancer, with a score of 48(40,55).Multivariate linear regression analysis showed that financial hardship, history of intestinal fistula, and introverted personality were all risk factors for patients' perception of discrimination (P<0.05). The patients' perception of discrimination was negatively correlated with HRQoL, five functional domains, overall health, symptom domains, and financial hardship (P<0.05). Conclusions　The widespread perception of discrimination is detrimental to the recovery and improvement of the quality of life of patients with colorectal cancer. Early identification and proactive, effective measures to address this issue are key to reducing the perception of discrimination and can serve as a starting point for further enhancing the health-related quality of life (HRQoL) of these patients in the future.

Key words: Colorectal cancer, Perceived discrimination, Physical and mental health, Health-Related Quality of Life, Intervention measures,  , Relevance