国际医药卫生导报 ›› 2025, Vol. 31 ›› Issue (7): 1157-1161.DOI: 10.3760/cma.j.cn441417-20240912-07021

• 论著 • 上一篇    下一篇

急性脑出血患者住院时间延长的影响因素分析

任常青  李惠平  杜振萍  王立新  伍世表   

  1. 广东省中医院神经重症科,广州 510120

  • 收稿日期:2024-09-12 出版日期:2025-04-01 发布日期:2025-04-18
  • 通讯作者: 伍世表,Email:wushibiao621@126.com
  • 基金资助:

    广东省医学科学技术研究基金(C2022096)

Analysis of influencing factors of prolonged length of hospital stay in patients with acute intracerebral hemorrhage 

Ren Changqing, Li Huiping, Du Zhenping, Wang Lixin, Wu Shibiao   

  1. Department of Neurocritical Care, Guangdong Hospital of Traditional Chinese Medicine, Guangzhou 510120, China

  • Received:2024-09-12 Online:2025-04-01 Published:2025-04-18
  • Contact: Wu Shibiao, Email: wushibiao621@126.com
  • Supported by:

    Guangdong Provincial Medical Research Fund (C2022096)

摘要:

目的 探讨急性脑出血患者住院时间延长的影响因素。方法 采用回顾性研究方法,纳入2019年5月至2021年5月广东省中医院大德路总院、芳村分院、大学城分院收治的急性脑出血患者310例,收集所有患者的基线资料及入院24 h内实验室数据,根据住院时间将患者分为未延长组(≤14 d)和延长组(>14 d)。未延长组211例中男142例,年龄(61.62±15.51)岁。延长组99例中男64例,年龄(63.39±15.12)岁。采用独立样本t检验、Mann-Whitney U检验、χ2检验、多因素logistic回归分析法,分析脑出血患者住院时间延长的独立影响因素。结果 310例脑出血患者平均住院时间为12 d。未延长组的住院费用为22 613.48(15 343.92,38 598.77)元,延长组为98 618.66(60 511.49,152 027.37)元,差异有统计学意义(Z=-11.194,P<0.001)。多因素logistic回归分析显示,手术(比值比=2.477,95%置信区间1.286~4.770)、合并卒中相关性肺炎(比值比=2.189,95%置信区间1.033~4.641)、院内死亡(比值比=0.073,95%置信区间0.021~0.249)、出院时非重残[改良Rankin量表(mRS)评分≤2分](比值比=0.244,95%置信区间0.110~0.539)均是脑出血患者住院时间延长的独立影响因素(均P<0.05)。结论 手术、合并卒中相关性肺炎、院内死亡、出院时非重残状态均与脑出血患者住院时间延长密切相关。

关键词:

脑出血, 住院时间, 住院费用, 影响因素

Abstract:

Objective To investigate the influencing factors of prolonged length of hospital stay (LOS) in patients with acute intracerebral hemorrhage (ICH). Methods This retrospective study included 310 patients with ICH in three branches of Guangdong Hospital of Traditional Chinese Medicine from May 2019 to May 2021. We recorded baseline data and laboratory data within 24 hours after admission. According to the LOS, the patients were divided into a prolonged group (>14 days) and a non-prolonged group (≤14 days). Among the 211 cases in the non-prolonged group, there were 142 males, aged (61.62±15.51) years. Among the 99 patients in the prolonged group, there were 64 males, aged (63.39±15.12) years. Independent sample t test, Mann-Whitney U test, χ2 test, and multivariate logistic regression analysis were used to analyze the independent influencing factors of prolonged LOS in ICH patients. Results Among the 310 ICH patients enrolled, the average LOS was 12 days. The hospitalization cost in the prolonged group was higher than that in the non-prolonged group [22 613.48 (15 343.92, 38 598.77) yuan vs. 98 618.66 (60 511.49, 152 027.37) yuan, Z=-11.194, P<0.001], accounting for 63.1% of the total hospitalization medical cost. Multivariate logistic regression analysis showed that surgery (OR=2.477, 95%CI 1.286-4.770), stroke-associated pneumonia (SAP) (OR=2.189, 95%CI 1.033-4.641), in-hospital death (OR=0.073, 95%CI 0.021-0.249), and discharge from hospital with non-severe disability [modified Rankin scale (mRS) score ≤2 points] (OR=0.244, 95%CI 0.110-0.539) were independent influencing factors for prolonged LOS in ICH patients (all P<0.05). Conclusions Surgery, in-hospital death, SAP, and discharge from hospital with non-severe disability are closely related to prolonged LOS in patients with ICH. To achieve the purpose of reducing invalid LOS, reducing the waste of medical resources, and reducing the burden on patients and society, we suggest optimizing the surgical procedure, preventing and treating SAP at an early stage, and using antibacterial drugs rationally. In addition, we should pay attention to early rehabilitation management and establish a stable two-way referral channel with rehabilitation hospitals.

Key words:

Intracerebral hemorrhage, Length of hospital stay, Hospitalization costs, Influencing factors