Abstract: Objective　To explore the effect of feeding related symptom group nursing based on Muzer model for patients with esophageal cancer undergoing concurrent chemoradiotherapy. Methods　A total of 103 patients with esophageal cancer who underwent concurrent chemoradiotherapy in The Third Affiliated Hospital of Henan University of Traditional Chinese Medicine from August 2018 to October 2020 were selected and grouped according to the random number table method. The control group consisted of 51 patients, 30 males and 21 females, aged (57.53±6.22) years; the observation group consisted of 52 patients, 32 males and 20 females, aged (58.00±6.57) years. The control group was given routine nursing, and the observation group was given feeding related symptom group intervention based on Muzer model. The remission rate of feeding related symptom group, body immunity, and nutritional indicators were compared between the two groups. χ² test was used for the count data, independent sample t test was used for inter-group comparison of the measurement data, and paired t test was used for intra-group comparison of the measurement data. Results　After intervention, the body weight, hemoglobin (Hb), and albumin (Alb) levels in the observation group were higher than those in the control group [(65.87±2.39) kg vs. (54.30±1.95) kg, (123.95±11.25) g/L vs. (103.76±8.75) g/L, (269.95±18.59) g/L vs. (204.77±15.23) g/L], with statistically significant differences (all P<0.05). After intervention, the remission rates of anorexia, nausea and vomiting, dry mouth, fatigue, distress and sadness, drowsiness, and sleep disorder and the levels of CD3⁺, CD4⁺, and CD4⁺/CD8⁺ in the observation group were higher than those in the control group, and the CD8⁺ level was lower than that in the control group (all P<0.05). Conclusion　The feeding related symptom group nursing based on Muzer model can effectively improve the nutritional status and immunity in patients with esophageal cancer undergoing concurrent chemoradiotherapy, and improve the remission degree of chemoradiotherapy related symptom group.

Key words: Muzer model, Esophageal cancer, Concurrent chemoradiotherapy

摘要： 目的　探究基于穆泽尔模型的摄食相关症状群护理模式应用于食管癌同步放化疗患者的效果。方法　选取河南中医药大学第三附属医院2018年8月至2020年10月收治的103例食管癌同步放化疗患者，根据随机数字表法分组。对照组51例，男30例、女21例，年龄（57.53±6.22）岁。观察组52例，男32例、女20例，年龄（58.00±6.57）岁。对照组给予常规护理，观察组给予基于穆泽尔模型的摄食相关症状群干预，对比两组患者摄食相关症状群缓解率、机体免疫力及营养指标。计数资料用χ²检验，计量资料组间比较用独立样本t检验，组内比较用配对t检验。结果　干预后观察组体质量、血红蛋白（Hb）、白蛋白（Alb）水平均高于对照组［（65.87±2.39）kg比（54.30±1.95）kg、（123.95±11.25）g/L比（103.76±8.75）g/L、（269.95±18.59）g/L比（204.77±15.23）g/L］，差异均有统计学意义（均P<0.05）；干预后观察组食欲不振、恶心呕吐、口干、疲乏、苦恼悲伤、昏昏欲睡、睡眠障碍缓解率及CD3⁺、CD4⁺、CD4⁺/CD8⁺水平均高于对照组，CD8⁺水平低于对照组（均P<0.05）。结论　基于穆泽尔模型的摄食相关症状群护理模式对食管癌同步放化疗患者进行干预，可有效改善营养状态、机体免疫力，提高放化疗相关症状群缓解程度。

关键词: 穆泽尔模型, 食管癌, 同步放化疗