Abstract:

Objective　To explore the drug features and formula rules of Chinese medicine in the treatment of adenoid hypertrophy, and to guide and promote rational clinical drug use. Methods　A total of 559 Chinese medicine prescriptions for children diagnosed with adenoid hypertrophy in Panyu Branch of Guangdong Women and Children Hospital from January 1 to December 31, 2022 were collected, and the data were statistically analyzed using Excel statistical software. Results　Among them, there were 357 (63.86%) boys and 202 (36.14%) girls, and there were 60 cases (10.73%) aged 1 to 3, 343 cases (61.36%) aged 4 to 6, 134 cases (23.97%) aged 7 to 9, and 22 cases (3.94%) aged over 10. The six syndrome types were: lung and spleen deficiency (22.54%, 126 cases), phlegm-dampness intertwined (20.04%, 112 cases), phlegm-heat obstructing the lung (18.78%, 105 cases), pathogenic stagnation in the nose (15.92%, 89 cases), spleen and stomach deficiency (13.95%, 78 cases), and diet stagnation (8.77%, 49 cases). A total of 201 Chinese herbs were selected for analysis, with the main channels being lung, spleen, and stomach; the most frequently used Chinese medicines were poria, pinellia, licorice, Fritillaria thunbergii, and Xinyi. The co-prescription of two herbs with the highest frequency was pinellia + poria (244); the co-prescription of three herbs with the highest frequency was pinellia + poria + dried orange peel (184). Conclusion　The drug use for the treatment of adenoid hypertrophy in children is mainly focused on expelling pathogens, opening orifices, strengthening qi and promoting digestion, and eliminating phlegm and dampness, which provides reference for clinical drug use.

Key words:

Adenoid hypertrophy, Children, Traditional Chinese medicine, Medication rule

摘要：

目的　探讨中药治疗腺样体肥大的用药特点及组方规律，促进临床合理用药。方法　收集广东省妇幼保健番禺院区2022年1月1日至12月31日诊断为腺样体肥大儿童的中药处方共计559张，数据采用Excel软件进行统计分析。结果　其中男357例（63.86%），女202例（36.14%）；1～3岁60例（10.73%）、4～6岁343例（61.36%）、7～9岁134例（23.97%）、10岁以上22例（3.94%）。6个证型依次为：肺脾两虚（22.54%、126例）、痰湿互结（20.04%、112例）、痰热壅肺（18.78%、105例）、邪滞鼻窍（15.92%、89例）、脾胃虚证（13.95%、78例）、饮食停滞（8.77%、49例）。筛选出201味中药进行分析，归经以肺、脾、胃经为主；使用频次较高的中药为茯苓、法半夏、甘草、浙贝母、辛夷；常用两味中药配伍以法半夏、茯苓配伍频数最高（244）；常用三味中药配伍以法半夏、茯苓、陈皮配伍频数最高（184）。结论　小儿腺样体肥大用药以祛邪通窍、益气健脾、化痰祛湿为主。

关键词:

腺样体肥大, 小儿, 中药, 用药规律