Abstract:

Objective　To explore the effects of Yinao decoction combined with embedded acupuncture on sleep quality and traditional Chinese medicine (TCM) syndrome score in children with enuresis due to lung and spleen deficiency. Methods　A total of 80 children with enuresis due to lung and spleen deficiency from Xi'an Traditional Chinese Medicine Hospital from January 2023 to January 2024 were randomly divided into a single group (40 cases) and a combined group (40 cases) according to the envelope drawing method. There were 21 boys and 19 girls in the single group, the age was (6.32±0.58) years old, and the course of disease was (2.33±0.17) years. In the combined group, there were 23 boys and 17 girls, the age was (6.36±0.52) years old, and the course of disease was (2.37±0.22) years. On the basis of conventional western medicine treatment, the single group received embedded acupuncture every other day, retaining the needle for 24 h each time. The combined group was treated with Yinao decoction on the basis of the single group, one dose a day, 200 ml of medicine juice was taken twice in the morning and evening. The treatment period of both groups was two months. The clinical efficacy, recurrence rate, and urodynamic parameters, TCM syndrome scores, sleep qualities, qualities of life, and monthly enuresis episodes before and after treatment were compared between the two groups. t test and χ² test were used for statistical analysis. Results　After treatment, the total effective rate of the combined group [97.5% (39/40)] was higher than that of the single group [80.0% (32/40)] (P<0.05); the bladder capacity [(302.31±28.33) ml], maximum urine flow rate [(16.13±1.58) ml/s], internal bladder pressure [(22.40±1.96) cmH₂O (1 cmH₂O=0.098 kPa)] were higher than those of the single group [(245.57±21.68) ml, (13.17±1.23) ml/s, and (16.18±1.47) cmH₂O], and the residual urine volume [(20.36±1.91) ml] was lower than that of the single group [(37.33±3.32) ml] (all P<0.05); the TCM syndrome scores of nocturnal enuresis, difficult to wake up during sleep, fatigue, cold limbs, and restless sleep were all lower than those of the single group (all P<0.05); the Pittsburgh Sleep Quality Index (PSQI) [(9.41±1.12) points] was lower than that of the single group [(12.38±1.47) points], and the Infant Subjective Life Quality Questionnaire (ISLQ) score [(182.33±20.46) points] was higher than that of the single group [(156.41±18.77) points] (all P<0.05); the monthly enuresis episodes [(3.22±0.37) times] and recurrence rate [2.5% (1/40)] were lower than those of the single group [(5.41±0.57) times and 15.0% (6/40)] (both P<0.05). Conclusion　Yinao decoction combined with embedded acupuncture significantly improves the sleep quality and TCM syndrome score in children with enuresis due to lung and spleen deficiency.

Key words:

Enuresis, Lung and spleen deficiency, Yinao , decoction, Embedded acupuncture, Sleep quality, Traditional Chinese medicine syndrome score, Children

摘要：

目的　探讨遗尿汤联合埋针治疗对肺脾两虚型遗尿症患儿睡眠质量及中医证候积分的影响。方法　选取2023年1月至2024年1月西安市中医医院收治的80例肺脾两虚型遗尿症患儿，按信封抽签法随机分为单一组（40例）和联合组（40例）。单一组男21例，女19例，年龄（6.32±0.58）岁，病程（2.33±0.17）年；联合组男23例，女17例，年龄（6.36±0.52）岁，病程（2.37±0.22）年。单一组在常规西医治疗基础上接受埋针治疗，每隔一天埋针一次，每次留针24 h。联合组在单一组基础上联合遗尿汤治疗，每日一剂，200 ml药汁分早晚两次温服。两组治疗周期均为两个月。比较两组临床疗效，治疗前后的尿流动力学、中医证候积分、睡眠质量、生活质量、月遗尿次数，复发率。采用t检验、χ²检验进行统计学分析。结果　治疗后，联合组的总有效率［97.5%（39/40）］高于单一组［80.0%（32/40）］（P<0.05）；膀胱容量［（302.31±28.33）ml］、最大尿流率［（16.13±1.58）ml/s］、膀胱内压［（22.40±1.96）cmH₂O（1 cmH₂O=0.098 kPa）］均大于单一组［（245.57±21.68）ml、（13.17±1.23）ml/s、（16.18±1.47）cmH₂O］，残余尿量［（20.36±1.91）ml］小于单一组［（37.33±3.32）ml］（均P<0.05）；睡中遗尿、熟睡不易醒、神疲乏力、肢凉怕冷、寐不安宁中医证候积分均低于单一组（均P<0.05）；匹兹堡睡眠质量指数（PSQI）［（9.41±1.12）分］低于单一组［（12.38±1.47）分］，少儿主观生活质量问卷（ISLQ）评分［（182.33±20.46）分］高于单一组［（156.41±18.77）分］（均P<0.05）；月遗尿次数［（3.22±0.37）次］和复发率［2.5%（1/40）］均低于单一组［（5.41±0.57）次、15.0%（6/40）］（均P<0.05）。结论　遗尿汤联合埋针治疗对肺脾两虚型遗尿症患儿睡眠质量及中医证候积分的改善作用较为显著。

关键词:

遗尿症, 肺脾两虚, 遗尿汤, 埋针, 睡眠质量, 中医证候积分, 儿童