Abstract:

This study retrospectively analyzed and explored the severe allergic shock phenomenon that occurred in two children during the pre-treatment stage of hematopoietic stem cell transplantation when using rabbit anti-human thymocyte immunoglobulin (rATG). Summary of experiences included: comprehensive evaluation of medical history, precise identification of allergic risk; standardizing the medication process and strictly implementing preventive measures; normalized emergency drills to ensure rapid and efficient rescue; implementing humanistic care to alleviate the anxiety. After timely and effective rescue treatment, both children successfully passed the pre-treatment phase of medication and completed hematopoietic stem cell transplantation surgery. They were improved and discharged at 28 and 23 days after surgery, respectively.

Key words:

Hematopoietic stem cell transplantation, Rabbit anti-human thymocyte immunoglobulin, Allergic shock, Nursing

摘要：

本研究回顾性分析2例患儿在造血干细胞移植预处理阶段中，使用兔抗人胸腺细胞免疫球蛋白（rATG）出现严重过敏性休克现象。经验总结包括：全面评估病史，精准识别过敏风险；规范用药流程，严格执行预防措施；常态化应急演练，确保快速高效抢救；实施人文关怀，缓解焦虑情绪。经过及时有效的抢救治疗，2例患儿均顺利度过预处理阶段，成功完成造血干细胞移植手术，分别在术后28 d和23 d好转出院。

关键词:

造血干细胞移植, 兔抗人胸腺细胞免疫球蛋白, 过敏性休克, 护理