Abstract:

Objective　To explore the research status, hotspots, and trends of cirrhosis sarcopenia, and to provide references for promoting the research of cirrhosis sarcopenia in China. Methods　The literatures retrieved from the Web of Science (WoS) TM core collection database from January 1, 2013 to September 2, 2023 and cited references were exported in the plain text format. The CiteSpace software was used to analyze the information of the research literatures on cirrhosis sarcopenia. Results　A total of 834 articles were included, and the number of articles on cirrhosis sarcopenia increased year by year in the past ten years. The United States and Japan were the core contributors to the literature, with not much cooperation between countries but closer cooperation between institutions. The main research hotspots on cirrhosis sarcopenia include the mechanism and treatment of sarcopenia, risk factors and effects, clinical studies on the relationship between sarcopenia and comorbidities such as liver cancer and hepatic encephalopathy, nutritional status, function, quality of life, etc. Conclusion　The research on sarcopenia in patients with cirrhosis is the developing trend in recent years, but there is still a lot of blank information. It lacks researches on sarcopenia in patients with cirrhosis in China. In the future, we can learn from foreign research experiences, pay attention to international cooperation, and strengthen in-depth researches on various aspects of sarcopenia in patients with cirrhosis.

Key words:

Cirrhosis, Sarcopenia, Web of Science, Visual analysis

摘要：

目的　探讨肝硬化肌少症的研究现状、热点及趋势，为促进我国肝硬化肌少症的研究提供借鉴。方法　检索时间2013-01-01至2023-09-02，将Web of Science （WoS） TM核心合集数据库检索到的文献与引用的参考文献以纯文本格式导出，采用CiteSpace软件，从而对肝硬化肌少症的研究文献进行信息分析研究。结果　共纳入834篇文献，近十年肝硬化肌少症的发文量逐年增加，美国和日本为文献的核心产出力量，国家间的合作较少而机构之间合作较为紧密。肝硬化肌少症主要的研究热点有肌少症的机制及治疗、危险因素及影响、肌少症与肝癌和肝性脑病等共病关系的临床研究、营养状况、功能及生活质量。结论　肝硬化患者肌少症方面的研究是近年来的发展趋势，目前仍有许多空白信息，我国对肝硬化肌少症患者的研究欠缺，未来可借鉴国外研究经验，注重国际合作，加强对肝硬化患者肌少症各方面的深入研究。

关键词:

肝硬化, 肌少症, Web of Science, 可视化分析