Abstract:

Objective　To investigate the effect of multi-sensory stimulation combined with repetitive transcranial magnetic stimulation in the treatment of children with language development delay/disorder. Methods　Ninety-one children with language development delay/disorder who were treated in Liaocheng People's Hospital from April 2019 to June 2022 were selected as the study objects, and were divided into a control group and an observation group according to the envelope method. In the control group, there were 28 boys and 17 girls, aged (2.89±0.79) years; in the observation group, there were 27 boys and 19 girls, aged (2.85±0.82) years. The control group received repetitive transcranial magnetic stimulation, and the observation group received multi-sensory stimulation on the basis. The therapeutic effect, oral motor score, pediatric Neuropsychological Development Scale (Gesell) score, verbal behavior score, and daily living ability score were compared between the two groups. Independent sample t test, paired t test, and χ² test were used. Results　The total effective rate was 95.65% (44/46) in the observation group and 80.00% (36/45) in the control group, with a statistically significant difference (χ²=5.244, P=0.022). After intervention, the scores of lip movement, jaw movement, and tongue movement in the two groups were higher than those before intervention (all P<0.05), the scores in the observation group were (17.62±3.15) points, (13.95±3.24) points, and (21.66±4.34) points, respectively, and the scores in the control group were (15.56±3.03) points, (12.07±3.12) points, and (19.30±3.94) points, respectively, with statistically significant differences (t=3.178, 2.819, and 2.714; P=0.002, 0.007, and 0.008). After intervention, the scores of motor ability, verbal ability, physical ability, and human ability of the two groups were higher than those before intervention (all P<0.05), the scores of the observation group were (85.87±3.68) points, (85.84±5.57) points, (81.54±7.13) points, and (84.56±6.81) points, respectively, and those of the control group were (83.46±3.70) points, (83.21±5.36) points, (75.37±7.22) points, and (81.01±6.73) points, respectively, with statistically significant differences (t=3.115, 2.294, 4.102, and 2.501; P=0.002, 0.024, <0.001, and 0.014). After intervention, the scores of verbal behavior and daily living ability of the two groups were higher than those before intervention (both P<0.05), and the scores of verbal behavior and daily living ability of the observation group were (42.26±5.63) points and (75.69±5.56) points, which were higher than those of the control group [(38.97±5.54) points and (72.39±5.37) points], with statistically significant differences (t=2.809 and 2.879, P=0.006 and 0.005). Conclusion　Multi-sensory stimulation combined with repetitive transcranial magnetic stimulation has better therapeutic effect in the treatment of children with language development delay/disorder, has higher oral motor score, developmental quotient, and verbal behavior score, and better daily living ability.

Key words:

Language development delay, Language disorder, Repetitive transcranial magnetic stimulation, Multisensory stimulation, Oral movement score, Pediatric Neuropsychological Development Scale

摘要：

目的　研究多感官刺激联合重复经颅磁刺激在儿童语言发育迟缓/障碍中的治疗效果。方法　选取2019年4月至2022年6月来聊城市人民医院治疗的91例语言发育迟缓/障碍患儿作为研究对象，依据信封法分为对照组和观察组。对照组45例中男28例，女17例，年龄（2.89±0.79）岁，采用重复经颅磁刺激治疗；观察组46例中男27例，女19例，年龄（2.85±0.82）岁，在对照组基础上采用多感官刺激治疗。比较两组患儿治疗效果、口部运动评分、小儿神经心理发育量表（Gesell）评分、语言行为评分以及日常生活能力评分。采用独立样本t检验、配对t检验、χ²检验。结果　观察组治疗总有效率为95.65%（44/46），对照组治疗总有效率为80.00%（36/45），差异有统计学意义（χ²=5.244，P=0.022）。干预后，两组口部运动的唇运动、下颚运动、舌运动评分均高于同组干预前（均P<0.05），观察组分别为（17.62±3.15）分、（13.95±3.24）分、（21.66±4.34）分，对照组分别为（15.56±3.03）分、（12.07±3.12）分、（19.30±3.94）分，差异均有统计学意义（t=3.178、2.819、2.714，P=0.002、0.007、0.008）。干预后两组动作能、应物能、语言能及应人能评分均高于干预前（均P<0.05），观察组分别为（85.87±3.68）分、（85.84±5.57）分、（81.54±7.13分）、（84.56±6.81）分，对照组分别为（83.46±3.70）分、（83.21±5.36）分、（75.37±7.22）分、（81.01±6.73）分，差异均有统计学意义（t=3.115、2.294、4.102、2.501，P=0.002、0.024、<0.001、0.014）。干预后两组语言行为评分及日常生活能力均高于干预前（均P<0.05），且观察组的语言行为评分为（42.26±5.63）分、日常生活能力评分为（75.69±5.56）分，高于对照组的（38.97±5.54）分、（72.39±5.37）分，差异均有统计学意义（t=2.809、2.879，P=0.006、0.005）。结论　多感官刺激联合重复经颅磁刺激治疗儿童语言发育迟缓/障碍，治疗效果更好，患儿口部运动评分、发育商及语言行为评分更高，患儿日常生活能力更好。

关键词:

语言发育迟缓, 语言障碍, 重复经颅磁刺激, 多感官刺激, 口部运动评分, 小儿神经心理发育量表