Effects of transcranial magnetic stimulation combined with walking and balance training on Parkinson's disease

doi:10.3760/cma.j.cn441417-20250223-20005

Abstract

Abstract:

Objective　To investigate the effect of transcranial magnetic stimulation (TMS) combined with walking and balance training on patients with Parkinson's disease (PD). Methods　In the prospective study, 150 PD patients diagnosed and treated in Henan Provincial People's Hospital from January 2023 to October 2024 were selected as the research objects. They were divided into two groups according to the random number table method, 75 cases in each group. There were 38 males and 37 females in the control group , aged (70.35±6.45) years old, and the course of disease was (1.05±0.35) years. There were 42 males and 33 females in the study group, aged (70.82±6.64) years old, and the course of disease was (1.48±0.58) years. Both groups received routine rehabilitation training, and the control group received targeted walking and balance training. The study group was treated with transcranial magnetic stimulation on the basis of the control group. Gait improvement, limb motor function [Fugl-Meyer Motor Function Assessment (FMA)], balance function and fall risk [Berg Balance Scale (BBS), Moese Fall Assessment Scale (MFS)], and cognitive function [ Montreal cognitive assessment scale (MoCA)] were compared before and after intervention. Statistical methods using t test. Result　After intervention, the step length, step width, step speed, FMA total score, BBS score, and MoCA score of the study group were higher than those of the control group [(48.29±4.63) cm vs. (40.55±4.38) cm, (15.66±2.93) cm vs. (14.32±2.61) cm, (1.69±0.34) km/h vs. (1.31 ± 0.22 ) km/h, and 161.74±15.95 vs. 150.62±12.33, 45.09±6.13 vs. 41.35±5.89, 25.06±3.45 vs. 22.87±2.78], and the step frequency, MFS scores were lower [(97.96±12.36) steps/min vs. (105.88±13.19) steps/min, 42.12±5.19 vs. 48.91±6.27], with statistical differences (all P<0.05). Conclusion　TMS combined walking and balance training can improve the gait of patients with Parkinson's disease, improve their balance function, reduce the degree of limb motor dysfunction, reduce the risk of fall, and effectively improve the cognitive function of patients.

Key words:

Parkinson's disease, Transcranial magnetic stimulation, Walking training, Balance training

摘要：

目的　探讨经颅磁刺激（TMS）联合步行、平衡训练对帕金森病（PD）患者的影响。方法　前瞻性研究，选取2023年1月至2024年10月在河南省人民医院诊治的150例PD患者作为研究对象，按照随机数字表法分为两组，各75例。对照组男38例、女37例，年龄（70.35±6.45）岁，病程（1.05±0.35）年；研究组男42例、女33例，年龄（70.82±6.64）岁，病程（1.48±0.58）年。两组均实施常规康复训练，对照组患者针对性实施步行及平衡训练；研究组在对照组基础上加用经颅磁刺激。对比两组患者干预前后步态改善情况、肢体运动功能［Fugl-Meyer运动功能评估量表（FMA）］、平衡功能与跌倒风险［Berg平衡量表（BBS）、Moese跌倒评估量表（MFS）］及认知功能［蒙特利尔认知评估量表（MoCA）］。统计学方法采用t检验。结果　干预后，研究组步长［（48.29±4.63）cm］、步宽［（15.66±2.93）cm］、步速［（1.69±0.34）km/h］、FMA总分［（161.74±15.95）分］、BBS评分［（45.09±6.13）分］、MoCA评分［（25.06±3.45）分］均高于对照组［（40.55±4.38）cm、（14.32±2.61）cm、（1.31±0.22）km/h、（150.62±12.33）分、（41.35±5.89）分、（22.87±2.78）分］，步频［（97.96±12.36）步/min］、MFS评分［（42.12±5.19）分］均低于对照组［（105.88±13.19）步/min、（48.91±6.27）分］，差异均有统计学意义（均P<0.05）。结论　TMS联合步行及平衡训练可促进PD患者步态改善，提高平衡功能，减轻肢体运动功能障碍程度，降低跌倒风险，改善患者认知功能。

关键词:

帕金森病, 经颅磁刺激, 步行训练, 平衡训练

Liu Zhenhuan, Yang Mengli, Zhu Yongxia, Ye Songyan, Zhang Shuang.

Effects of transcranial magnetic stimulation combined with walking and balance training on Parkinson's disease [J]. International Medicine and Health Guidance News, 2025, 31(20): 3364-3368.

刘振环杨孟丽朱永霞叶松岩张爽.

经颅磁刺激联合步行及平衡训练对帕金森病患者的影响 [J]. 国际医药卫生导报, 2025, 31(20): 3364-3368.

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