Abstract:

Objective　To evaluate the clinical efficacy of the Wuxing Sanbu acupuncture method for limb dysfunction in patients with acute cerebral infarction (ACI). Methods　A total of 112 ACI patients with limb dysfunction treated in Lianyungang Affiliated Hospital of Nanjing University of Traditional Chinese Medicine from October 2022 to October 2024 were selected for the randomized controlled trial, and were divided into a study group and a control group by the random number table method, with 56 cases in each group. There were 30 males and 26 females in the control group who were (65.68±12.28) years old. There were 34 males and 22 females in the study group who were (64.21±13.15) years old. The control group took conventional western drugs and rehabilitation therapy; in addition, the study group took Wuxing Sanbu acupuncture. After 2 weeks' treatment, the clinical outcomes were assessed using the modified Rankin Scale (mRS), National Institutes of Health Stroke Scale (NIHSS), Fugl-Meyer Assessment (FMA), and hypersensitive C-reactive protein (hs-CRP). The t test, nonparametric test, and χ² test or Fisher precision probability test were used for the statistical comparisons. Results　After the treatment, the scores of NIHSS and FMA were better than those before the treatment in both groups, and those in the study group were better than those in the control group [2 (1, 3) vs. 3 (2, 5) and 69.07±14.92 vs. 60.34±17.11], with statistical differences (both P<0.05). After the treatment, the score of mRS and the proportion of the patients with favorable neurological recovery in the study group were better than those in the control group [ 1 (1, 2) vs. 2 (1, 3) and 83.93% (47/56) vs. 66.07% (37/56)], with statistical differences (both P<0.05). After the treatment, the levels of hs-CRP in both groups were lower than those before the treatment, and the level in the study group was lower than that in the control group [1.25 (0.47, 2.21) mg/L vs. 1.77 (0.95, 3.21) mg/L], with a statistical difference (P < 0.05). Conclusion　Routine treatment combined with Wuxing Sanbu acupuncture can improve the limb dysfunction of patients with ACI, promote their neurological recovery, reduce systemic inflammation, and improve their prognosis.

Key words:

Cerebral infarction, Wuxing Sanbu , acupuncture method, Limb dysfunction, Inflammatory reaction

摘要：

目的　探讨五行三部针法治疗急性脑梗死患者肢体功能障碍的临床疗效。方法　采用随机对照研究，选取2022年11月至2024年11月南京中医药大学连云港附属医院收治的急性脑梗死肢体功能障碍患者112例，随机数字表法分为研究组和对照组，各56例。对照组中男30例，女26例，年龄（65.68±12.28）岁。研究组中男34例，女22例，年龄（64.21±13.15）岁。对照组给予常规西药及康复治疗，研究组在对照组的基础上给予五行三部针法治疗，治疗2周后采用美国国立卫生研究院卒中量表（NIHSS）、Fugl-Meyer评分（FMA）、改良Rankin量表（mRS）和超敏C反应蛋白（hs-CRP）水平评估临床结局。采用t检验、非参数检验、χ²检验或Fisher确切概率法进行统计比较。结果　治疗后两组NIHSS、FMA评分均优于治疗前，且研究组优于对照组［2（1，3）分比3（2，5）分、（69.07±14.92）分比（60.34±17.11）分］，差异均有统计学意义（均P<0.05）。治疗后研究组mRS评分［1（1，2）分］低于对照组［2（1，3）分］，神经功能恢复预后良好比例［83.93%（47/56）］高于对照组［66.07%（37/56）］，差异均有统计学意义（均P<0.05）。治疗后两组hs-CRP水平低于治疗前，且研究组低于对照组［1.25（0.47，2.21）mg/L比1.77（0.95，3.21）mg/L］，差异有统计学意义（P<0.05）。结论　在常规治疗基础上，五行三部针法可进一步改善急性脑梗死患者肢体功能障碍，促进神经功能恢复，降低炎症反应，改善预后。

关键词:

脑梗死, 五行三部针法, 肢体功能障碍, 炎症反应