Abstract:

Objective　To explore the impact of compound hydrochloride articaine on pain level and anesthetic effect in the treatment of dental pulp diseases in children. Methods　This study was a randomized controlled trial. A total of 80 children with dental pulp diseases who were admitted to Liaocheng Third People's Hospital from January 2020 to January 2023 were selected as the research subjects. They were divided into a control group and an observation group using the random number table method with 40 cases in each group. In the control group, there were 22 boys and 18 girls, aged 5 to 11 (7.72±1.13) years. In the observation group, there were 21 boys and 19 girls, aged 5 to 12 (7.58±1.05) years. The control group underwent anesthesia treatment with lidocaine, while the observation group underwent anesthesia treatment with compound hydrochloride articaine. The anesthesia effect (onset time of anesthesia, duration of anesthesia, and recovery time after anesthesia), anesthesia efficiency, pain degree [Visual Analog Scale (VAS) scores during surgery and during anesthesia], and incidence of adverse reactions (gingival pain, nausea and vomiting, dizziness and headache, and tachycardia) were compared between the two groups. Independent sample t test and χ² test were used. Results　The onset time of anesthesia in the observation group was (2.19±0.33) min and the recovery time after anesthesia was (155.71±26.17) min, which were shorter than those in the control group [(5.56±1.10) min and (172.15±27.69) min]; the duration of anesthesia was longer than that in the control group [(156.78±25.26) min vs. (141.57±19.82) min], with statistically significant differences (all P<0.05). The total effective rate of anesthesia in the observation group [97.5% (39/40)] was higher than that in the control group [62.5% (25/40)], with a statistically significant difference (P<0.05). The VAS scores during surgery [(1.16±0.25)] and during anesthesia [(1.69±0.37)] in the observation group were lower than those in the control group [(2.36±0.53) and (2.48±0.57)], with statistically significant differences (both P<0.05). The total incidence of adverse reactions in the observation group [12.5% (5/40)] was lower than that in the control group [45.0% (18/40)], with a statistically significant difference (P=0.001). Conclusion　Compound hydrochloride articaine can reduce the pain level and enhance the anesthetic effect in the treatment of dental pulp diseases in children.

Key words:

Compound hydrochloride articaine, Lidocaine, Dental pulp diseases, Anesthetic effect, Pain level, Adverse reactions

摘要：

目的　探究复方盐酸阿替卡因对儿童牙体牙髓疾病治疗中的疼痛程度、麻醉效果的影响。方法　本研究为随机对照试验，选取2020年1月至2023年1月聊城市第三人民医院纳入的80例牙体牙髓疾病患儿作为研究对象，采用随机数字表法分为对照组和观察组，各40例。对照组男22例，女18例，年龄5～11（7.72±1.13）岁；观察组男21例，女19例，年龄5～12（7.58±1.05）岁。对照组行利多卡因进行麻醉治疗，观察组行复方盐酸阿替卡因进行麻醉治疗。比较两组的麻醉效果（麻醉起效时间、麻醉持续时间、麻醉后恢复时间）、麻醉有效率、疼痛程度［手术期间、麻醉期间视觉模拟量表（VAS）评分］、不良反应发生情况（牙龈肿痛、恶心呕吐、头晕头痛、心跳加速）。采用独立样本t检验和χ²检验。结果　观察组麻醉起效时间（2.19±0.33）min、麻醉后恢复时间（155.71±26.17）min均短于对照组（5.56±1.10）min、（172.15±27.69）min，麻醉持续时间（156.78±25.26）min长于对照组（141.57±19.82）min，差异均有统计学意义（均P<0.05）；观察组麻醉总有效率［97.5%（39/40）］高于对照组［62.5%（25/40）］，差异有统计学意义（P<0.05）；观察组患儿手术期间VAS评分（1.16±0.25）分、麻醉期间VAS评分（1.69±0.37）分均低于对照组（2.36±0.53）分、（2.48±0.57）分，差异均有统计学意义（均P<0.05）；观察组患儿不良反应总发生率［12.5%（5/40）］低于对照组［45.0%（18/40）］，差异有统计学意义（P=0.001）。结论　复方盐酸阿替卡因可以降低儿童牙体牙髓疾病治疗中的疼痛程度、增强麻醉效果。

关键词:

复方盐酸阿替卡因, 利多卡因, 牙体牙髓疾病, 麻醉效果, 疼痛程度, 不良反应