Abstract:

Objective　 To study the distribution of traditional Chinese medicine syndromes in patients with diabetic gastroparesis (DGP), to analyze the characteristics of traditional Chinese medicine syndromes in patients with DGP, and to provide references for the clinical differentiation and treatment.Methods　A total of 153 patients with DGP treated at Ankang Hospital of Traditional Chinese Medicine from May 2021 to November 2023 were investigated by the general data investigation table and traditional Chinese medicine syndrome collection table, including 66 males and 87 females who were (51.30±10.28) years old. The descriptive frequency analysis and cluster analysis were applied. The χ² test was used. Results　The syndrome analysis showed that spleen and stomach weakness syndrome accounted for the highest proportion (56 cases, 36.60%), followed by liver depression and spleen deficiency syndrome (31 cases, 20.26%), phlegm-dampness syndrome (28 cases, 18.30%), cold and heat syndrome (21 cases, 13.73%), and Yin deficiency and internal heat syndrome (17 cases, 11.11%). The analysis of the relationship between the syndromes and diabetes course showed that the patients with diabetes course within 5 years mainly had cold and heat syndrome (16 cases, 28.07%) and phlegm-dampness syndrome (15 cases, 26.32%); the patients with diabetes course >5-10 years mainly had spleen and stomach weakness syndrome (17 cases, 41.46%) and liver depression and spleen deficiency syndrome (10 cases, 24.39%); the patients with diabetes course over 10 years mainly had spleen and stomach weakness syndrome (29, 52.73%) and Yin deficiency and internal heat syndrome (10 cases, 18.18%). Conclusions　The main traditional Chinese medicine syndrome of patients with DGP is spleen and stomach weakness, which runs through the whole process of DGP development. With the extension of diabetes course, the patients' pathogenesis is the evolution process from deficiency to deficiency syndrome. 

Key words:

Syndromes, Diabetic gastroparesis, Spleen and stomach weakness syndrome, Disease course

摘要：

目的　研究糖尿病胃轻瘫（diabetic gastroparesis，DGP）患者的中医证候分布规律，分析DGP患者中医证候分布特点，为临床辨治提供参考。方法　使用一般资料调查表、中医证候采集表对2021年5月至2023年11月在安康市中医医院就诊的153例DGP患者行问卷调查，其中男66例，女87例，年龄（51.30±10.28）岁。统计学方法采用描述性频数分析和聚类分析。采用χ²检验。结果　证候分析显示，脾胃虚弱证占比最高（56例，36.60%），其次为肝郁脾虚证（31例，20.26%）、痰湿内蕴证（28例，18.30%）、寒热错杂证（21例，13.73%），阴虚内热证最少（17例，11.11%）。证候与糖尿病病程的关系分析显示：糖尿病病程5年以内的患者以寒热错杂证（16例，28.07%）、痰湿内蕴证（15例，26.32%）为主，病程>5～10年的患者以脾胃虚弱证（17例，41.46%）、肝郁脾虚证（10例，24.39%）为主，病程>10年的患者以脾胃虚弱证（29例，52.73%）、阴虚内热证（10例，18.18%）为主。结论　DGP患者的中医证候以脾胃虚弱为主，脾胃虚弱贯穿了DGP发展的全过程。随着糖尿病病程的延长，患者的病机表现为由虚实夹杂向虚证演化的过程。

关键词:

证候, 糖尿病胃轻瘫, 脾胃虚弱证, 病程