Research progress of Parkinson's disease 7 gene in renal diseases

doi:10.3760/cma.j.issn.1007-1245.2023.22.004

Abstract

Abstract:

Parkinson's disease 7 (PARK7) gene widely exists in prokaryotes and eukaryotes. PARK7 protein is a functional protein that exists in cells and has a wide range of anti-oxidative stress effects. It mainly involves in neural, reproductive, and cardiovascular diseases and tumors. At present, there are just a few researches on the progress of PARK7 in kidney diseases. This paper mainly focuses on PARK7 gene's structural biology, physiological function, and its relationship with kidney diseases.

Key words:

Gene, Parkinson's disease 7, Kidney, Function, Progress

摘要：

重组人帕金森蛋白7（PARK7）基因广泛存在于原核及真核生物，PARK7蛋白是一种广泛存在于细胞内的功能蛋白，具有广泛的抗氧化应激作用，报道多见其参与神经、生殖、心血管及肿瘤相关等疾病。目前，关于PARK7在肾脏疾病中的研究进展尚少，本文主要通过对PARK7基因的结构生物学、生理功能及机制进行分析，并阐述PARK7基因与肾脏疾病的关系及其研究进展。

关键词:

基因, 重组人帕金森蛋白7, 肾脏, 功能, 进展

Tan Junjie, Jiang Xinxin.

Research progress of Parkinson's disease 7 gene in renal diseases [J]. International Medicine and Health Guidance News, 2023, 29(22): 3166-3170.

谭俊杰江欣欣.

重组人帕金森蛋白7基因在肾脏疾病中的研究进展 [J]. 国际医药卫生导报, 2023, 29(22): 3166-3170.

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