Abstract:

 Blastic plasmacytoid dendritic cell neoplasm is a rare and invasive hematological malignant tumor derived from precursors of plasmacytoid dendritic cells. We reported a case of cutaneous blastic plasmacytoid dendritic cell neoplasm complicated with bone marrow chronic myelomonocytic leukemia which was presented with multiple skin nodules admitted to The Second Affiliated Hospital of Fujian Medical University in May 2020, and the definite diagnosis was obtained combined with the skin pathology, immunohistochemistry, bone marrow cytology, flow cytometry, and gene detection.

Key words: Blastic plasmacytoid dendritic cell neoplasm, Chronic myelomonocytic leukemia, Prognostic gene

摘要： 母细胞性浆细胞样树突细胞肿瘤是一种来源于浆细胞样树突状细胞前体的侵袭性血液系统恶性肿瘤，临床罕见。本文报道2020年5月福建医科大学附属第二医院收治的1例皮肤母细胞性浆细胞样树突细胞肿瘤合并骨髓慢性粒-单核细胞白血病病例，该患者以皮肤多发结节起病，结合皮肤病理、免疫组化、骨髓细胞学、流式及基因检测获得明确诊断。

关键词: 母细胞性浆细胞样树突细胞肿瘤, 慢性粒-单核细胞白血病, 预后基因