Effect of bioimpedance analysis-guided ultrafiltration on remaining renal function in hemodialysis patients: a meta-analysis

doi:10.3760/cma.j.issn.1007-1245.2024.08.015

Abstract

Abstract:

Objective　To investigate the effect of bioimpedance analysis (BIA) -guided ultrafiltration on remaining renal function (RRF) in hemodialysis patients compared with conventional clinical methods. Methods　PubMed, Cochrane Library, Embase, Web of Science, CNKI, Wanfang, VIP, and CBM were searched for randomized controlled trials (RCTs) about the effects of BIA-guided ultrafiltration on RRF in hemodialysis patients compared with conventional clinical methods from the inception to December 31, 2022. Meta-analysis was performed by RevMan 5.4. Results　A total of 6 RCTs with 406 participants were included. The results of meta-analysis showed that the RRF [P<0.05, MD=1.15, 95%CI (1.00, 1.31)] and 24 h urine output [P<0.05, MD=253.56, 95%CI (229.17, 277.96)] of the BIA guidance group were higher than those of the control group, and the ultrafiltration volume [P<0.05, MD=-0.45, 95%CI (-0.65, -0.26)] and diastolic blood pressure [P<0.05, MD=-5.52, 95%CI (-7.58, -3.47)] were lower than those of the control group, but there were no statistically significant differences in the systolic blood pressure [P>0.05, MD=-0.25, 95%CI (-7.70, 7.21)], body weight [P>0.05, MD=-0.01, 95%CI (-3.38, 3.37)], or albumin [P>0.05, MD=0.41, 95%CI (-1.61, 2.43)] between the two groups. Conclusion　Based on the existed data, compared with conventional clinical methods, BIA-guided ultrafiltration can protect the RRF in hemodialysis patients.

Key words:

Hemodialysis, Residual renal function, Bioimpedance analysis, Meta-analysis

摘要：

目的　探讨生物电阻抗分析法（BIA）指导超滤量同常规临床方法相比对血液透析患者残余肾功能（RRF）的影响。方法　计算机检索2022年12月31日前发表在PubMed、Cochrane Library、Embase、Web of Science等英文数据库以及中国知网、维普数据库、万方医学和中国生物医学文献数据库等中文数据库，探讨应用BIA指导超滤量同常规临床方法相比对血液透析患者RRF影响的随机对照试验（RCT），采用RevMan 5.4软件进行meta分析。结果　最终纳入6篇文献，共计406名受试者。meta分析结果显示随访结束后BIA指导组的患者RRF（P<0.05，MD=1.15，95%CI：1.00～1.31）、24 h尿量（P<0.05，MD=253.56，95%CI：229.17～277.96）均高于对照组，超滤量（P<0.05，MD=-0.45，95%CI：-0.65～-0.26）及舒张压（P<0.05，MD=-5.52，95%CI：-7.58～-3.47）均低于对照组；两组患者的收缩压（P>0.05，MD=-0.25，95%CI：-7.70～7.21）、体质量（P>0.05，MD=-0.01，95%CI：-3.38～3.37）、白蛋白（P>0.05，MD=0.41，95%CI：-1.61～2.43）比较，差异均无统计学意义。结论　基于现有研究，在营养管理及容量管理过程中采用BIA指导超滤量同常规临床方法相比有助于保护血液透析患者的RRF。

关键词:

血液透析, 残余肾功能, 生物电阻抗分析, meta分析

Jiang Haili, Pan Hong, Jiao Chunxiao, Cong Lina, Li Haiqiang.

Effect of bioimpedance analysis-guided ultrafiltration on remaining renal function in hemodialysis patients: a meta-analysis [J]. International Medicine and Health Guidance News, 2024, 30(8): 1301-1306.

蒋海丽潘虹矫春晓丛丽娜李海强.

BIA指导血液透析对患者RRF影响的meta分析 [J]. 国际医药卫生导报, 2024, 30(8): 1301-1306.

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