Research progress of PI3K/AKT signaling pathway in cardiovascular disease

doi:10.3760/cma.j.issn.1007-1245.2023.15.002

Abstract

Abstract:

Cardiovascular disease refers to various lesions of the cardiovascular system, mainly including coronary heart disease, heart failure, hypertension, etc., and has become the first major death disease in China. The phosphatidyl inositol 3-kinase/protein kinase B (PI3K/AKT) signaling pathway is one of the important metabolic pathways and plays an important role in the cardiovascular system. This article reviews the research progress of PI3K/AKT signaling pathway in cardiovascular disease.

Key words:

Myocardial infarction, Diabetic cardiomyopathy, Atrial fibrillation, Hypertension, PI3K/AKT signaling pathway, Progress

摘要：

心血管疾病是指心血管系统所发生的各种病变，主要包括冠心病、心力衰竭、高血压等，已成为中国第一大致死疾病。磷脂酰肌醇3-激酶/蛋白激酶B（PI3K/AKT）信号通路是重要的代谢通路，在心血管系统中发挥重要作用。本文就PI3K/AKT信号通路在心血管疾病中的研究进展进行综述。

关键词:

心肌梗死, 糖尿病心肌病, 心房颤动, 高血压, PI3K/AKT信号通路, 进展

Zhao Jiahao, Shang Xue, Zhu Hui, Li Xinxi, Xu Huipu.

Research progress of PI3K/AKT signaling pathway in cardiovascular disease [J]. International Medicine and Health Guidance News, 2023, 29(15): 2077-2080.

赵嘉昊商雪祝慧李昕玺徐会圃.

PI3K/AKT信号通路在心血管疾病中的研究进展 [J]. 国际医药卫生导报, 2023, 29(15): 2077-2080.

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