Abstract:

Objective　To retrospectively analyze the clinical data of COVID-19 variant Omicron infection in Shanghai Songjiang Shelter Hospital, and to understand the rationality of drug use for Omicron infection. Methods　The clinical information of 1 059 patients with Omicron infection in Shanghai Songjiang Shelter Hospital from April 1 to May 15, 2022 was collected. The basic information (gender and age), clinical diagnosis and medication, hospitalization duration, outcomes, and discharge of the infected patients were analyzed using descriptive analysis. Results　Among the 1 059 cases of Omicron infection, there were 538 males (50.80%) and 521 females (49.20%). Twenty-one cases (1.98%) had basic diseases. The clinical diagnosis was mild in 87 cases (8.22%); 972 cases (91.78%) had no symptoms. According to the characteristics of Omicron variant, Chinese patent medicine and traditional Chinese medicine are mainly used in Shanghai Songjiang Shelter Hospital for drug treatment, including Lianhua Qingwen Granules, Shenling Baisu Granules, Shenling Jianpi Granules, etc., and the prescription of decoction and medicine is used for synergistic treatment, which has achieved very good therapeutic effect. Conclusions　The medication of patients infected with Omicron in Shanghai Songjiang Shelter Hospital was basically reasonable and in line with the relevant requirements in the COVID-19 Diagnosis and Treatment Program (Trial Version 9). Chinese medicine has a definite curative effect and small adverse reactions in the treatment of patients infected with Omicron and the prevention of infection, but there are still some problems in the combination of drugs under different situations, and we need to strengthen supervision to avoid increasing the adverse reactions.

Key words:

COVID-19, Omicron mutant, Shelter hospital, Medication analysis

摘要：

目的　回顾分析上海松江方舱医院新型冠状病毒变异株奥密克戎（Omicron）感染者的临床资料，了解Omicron感染者的用药合理性。方法　收集2022年4月1日至5月15日上海松江方舱医院1 059例Omicron感染者临床信息，采用描述性分析方法，分析感染者的基本信息（性别、年龄）、临床诊断及用药、住院时间、转归出院等。结果　1 059例Omicron感染者中，男538例（50.80%），女521例（49.20%）；有基础疾病者21例（1.98%）。临床诊断轻症87例（8.22%）、无症状972例（91.78%）。针对Omicron变异株的特点，药物治疗上方舱医院以中成药及中药方剂为主，包括连花清瘟颗粒、参苓白术颗粒、参苓健脾胃颗粒等，以及使用汤药协定方加以协同治疗，取得了非常好的治疗效果。结论　松江方舱医院Omicron感染者的用药基本合理，符合《新型冠状病毒肺炎诊疗方案（试行第九版）》中的相关要求。中药在治疗Omicron感染者以及预防感染方面疗效确切，不良反应小，不过不同情况下药物联用方面仍然存在一些问题，需要加强监护，以免增加不良反应。

关键词:

新型冠状病毒, 奥密克戎变异株, 方舱医院, 用药分析