Abstract:

Objective　To observe the clinical effect of music therapy combined with cognitive behavioral intervention in children with benign epilepsy with centro-temporal spikes (BECT). Methods　Carry out a prospective study.A total of 86 children with BECT who were admitted to the Pediatrics Department of Henan Provincial People's Hospital from March 2021 to September 2024 were selected as the research subjects. They were divided into two groups by convenience sampling method, with 43 cases in each group.Control group: 22 males and 21 females, aged 6 to 13 (9.24±1.21) years, with a disease duration of 3 to 12 (7.57±1.42) months;Carry out routine intervention;Observation group: 23 males and 20 females, aged 6 to 14 (9.33±1.17) years, with a disease duration of 3 to 13 (7.65±1.39) months;On the basis of the control group, music therapy combined with cognitive behavioral intervention was implemented, and the intervention lasted for 3 months continuously.Both groups received continuous intervention for 3 months.The cognitive functions, negative emotions, medication compliance and developmental quotient of the two groups of BECT patients were compared before and after the intervention.The statistical method employed was the t-test. Results　After the intervention, the verbal comprehension index, working memory index, perceptual reasoning index, and processing speed index of the children in the observation group all increased compared to those before the intervention, while those in the control group were lower than those in the observation group (t=-3.577,-3.607,-5.276,-2.513;all P<0.05).The scores of the Screening Scale for Anxiety-Related Emotional Disorders in Children (SCARED) and the Depression Self-Rating Scale for Children (DSRSC) in the control group were both higher than those in the observation group [(26.51±3.62) points vs. (20.32±2.53) points, (16.58±1.58)points vs.(12.62±1.37)points ], and the differences were statistically significant (t=9.191,12.417; both P<0.05).After the intervention, the scores of the medication compliance scale, fine motor skills, gross motor skills, adaptability, language, and personal-social aspects in the control group were all lower than those in the observation group, and the differences were statistically significant (t=-5.451,-2.872,-4.016,-4.564,-3.095,-2.329; all P<0.05). Conclusion　For children with BECT, the application of music therapy combined with cognitive behavioral intervention can effectively improve their cognitive levels and negative emotions, as well as enhance their medication compliance and developmental quotient.

Key words:

Benign childhood epilepsy with central temporal spikes, Music therapy, Cognitive behavioral intervention, Cognitive function, Drug compliance, Medicine compliance, Anxiety and depression, Children

摘要：

目的　观察对良性癫痫伴中央颞区棘波（BECT）患儿应用音乐疗法联合认知行为干预的临床效果。方法　采用前瞻性研究。选取河南省人民医院儿科2021年3月至2024年9月收治的86例BECT患儿作为研究对象，采用便利抽样法分为两组，每组43例。对照组：男22例，女21例，年龄6～13（9.24±1.21）岁，病程3～12（7.57±1.42）个月；予以常规干预。观察组：男23例，女20例，年龄6～14（9.33±1.17）岁，病程3～13（7.65±1.39）个月；在对照组的基础上予以音乐疗法联合认知行为干预。两组均连续干预3个月。比较两组BECT患儿干预前后认知功能、负面情绪、服药依从性及发育商情况。统计学方法采用t检验。结果　干预后，观察组患儿言语理解、工作记忆、知觉推理、加工速度指数均较干预前升高，对照组均低于观察组（t=-3.577、-3.607、-5.276、-2.513，均P<0.05）；对照组儿童焦虑性情绪障碍筛查表（SCARED）、儿童抑郁障碍自评量表（DSRSC）得分均高于观察组［（26.51±3.62）分比（20.32±2.53）分、（16.58±1.58）分比（12.62±1.37）分］，差异均有统计学意义（t=9.191、12.417，均P<0.05）。干预后，对照组服药依从性量表、精细运动、大运动、适应性、语言、个人-社交评分均低于观察组，差异有统计学意义（t=-5.451、-2.872、-4.016、-4.564、-3.095、-2.329，均P<0.05）。结论　BECT患儿应用音乐疗法联合认知行为干预能有效改善认知水平和负面情绪，提高服药依从性及发育商。

关键词:

良性癫痫伴中央颞区棘波, 音乐疗法, 认知行为干预, 认知功能, 服药依从性, 焦虑抑郁, 儿童