Abstract:

Objective　To investigate the effect of traditional Chinese medicine (TCM) package combined with pulmonary rehabilitation training on patients with stable chronic obstructive pulmonary disease (COPD). Methods　A total of 98 patients with stable COPD admitted to Zhumadian Hospital of Traditional Chinese Medicine from October 2022 to October 2024 were selected for a prospective study. They were divided into two groups according to the random number table method, with 49 patients in each group. In the control group, there were 22 females and 27 males; the age ranged from 48 to 72 years old [(60.00±3.54) years old]; the disease duration was 2 to 16 years [(9.98±1.13) years]. In the observation group, there were 21 females and 28 males; the age ranged from 46 to 74 years old [(60.13±3.56) years old]; the disease duration was 1 to 17 years [(9.95±1.16) years]. The control group received routine nursing care and pulmonary rehabilitation training, and the observation group received TCM package intervention on the basis of the control group. Both groups were continuously intervened and observed for 2 weeks. The dyspnea symptoms, exercise endurance, pulmonary function, and quality of life were compared between the two groups. Statistical analysis was conducted using the χ² test and t test. Results　After intervention, the score of the modified Medical Research Council (mMRC) dyspnea scale in the observation group was (1.64±0.17) points, which was lower than that in the control group [(2.18±0.20) points]; the distance of the 6-minute walk test (6MWT) was (435.67±15.62) m, which was longer than that in the control group [(390.79±15.51) m] (t=14.401 and 14.272, both P<0.05). After intervention, the forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), and FEV1/FVC in the observation group were (3.13±0.40) L, (2.30±0.39) L, and (73.48±9.75)%, which were all higher than those in the control group [(2.95±0.36) L, (2.05±0.36) L, and (69.49±9.72)%] (t=2.341, 3.297, and 2.029, all P<0.05). After intervention, the scores of poor sleep quality, dyspnea, cough, expectoration, limited activity ability, lack of energy, psychological impact, and limited outdoor activity of the COPD Assessment Test (CAT) in the observation group were (1.01±0.21) points, (1.12±0.24) points, (1.10±0.11) points, (1.12±0.19) points, (1.12±0.21) points, (1.15±0.23) points, (1.13±0.16) points, and (1.13±0.15) points, which were all lower than those in the control group [(1.34±0.26) points, (2.21±0.35) points, (2.13±0.14) points, (1.53±0.22) points, (2.04±0.28) points, (2.94±0.26) points, (2.57±0.20) points, and (1.76±0.18) points] (t=6.912, 17.979, 40.495, 9.873, 18.400, 36.096, 39.356, and 18.821, all P<0.05). Conclusion　TCM package combined with pulmonary rehabilitation training can alleviate the dyspnea symptoms in stable COPD patients, enhance the exercise endurance, improve the pulmonary function, and contributes to improving the quality of life.

Key words:

Chronic obstructive pulmonary disease, Traditional Chinese medicine package, Pulmonary rehabilitation training, Symptoms of dyspnea, Exercise endurance, Pulmonary function

摘要：

目的　探讨中药封包联合肺康复训练在稳定期慢性阻塞性肺疾病（COPD）患者中的应用效果。方法　选取驻马店市中医院2022年10月至2024年10月收治的稳定期COPD患者98例进行前瞻性研究，按随机数字表法将其分为两组，每组49例。对照组女22例，男27例；年龄48～72（60.00±3.54）岁；病程2～16（9.98±1.13）年。观察组女21例，男28例；年龄46～74（60.13±3.56）岁；病程1～17（9.95±1.16）年。对照组采取常规护理和肺康复训练干预，观察组在对照组基础上采取中药封包干预，两组均连续干预观察2周。比较两组呼吸困难症状、运动耐力、肺功能以及生活质量。采用χ²检验、t检验进行统计学分析。结果　观察组干预后改良版呼吸困难量表（mMRc）评分为（1.64±0.17）分，低于对照组的（2.18±0.20）分，6 min步行实验（6MWT）为（435.67±15.62）m，长于对照组的（390.79±15.51）m（t=14.401、14.272，均P<0.05）；观察组干预后用力肺活量（FVC）、第一秒用力呼气容积（FEV1）、FEV1/FVC分别为（3.13±0.40）L、（2.30±0.39）L、（73.48±9.75）%，均高于对照组的（2.95±0.36）L、（2.05±0.36）L、（69.49±9.72）%（t=2.341、3.297、2.029，均P<0.05）；观察组干预后慢阻肺评估测试（CAT）中睡眠质量差、呼吸困难、咳嗽、咳痰、活动能力受限、精力不足、心理影响、外出活动受限评分分别为（1.01±0.21）分、（1.12±0.24）分、（1.10±0.11）分、（1.12±0.19）分、（1.12±0.21）分、（1.15±0.23）分、（1.13±0.16）分、（1.13±0.15）分，均低于对照组的（1.34±0.26）分、（2.21±0.35）分、（2.13±0.14）分、（1.53±0.22）分、（2.04±0.28）分、（2.94±0.26）分、（2.57±0.20）分、（1.76±0.18）分（t=6.912、17.979、40.495、9.873、18.400、36.096、39.356、18.821，均P<0.05）。结论　中药封包联合肺康复训练能够缓解稳定期COPD患者呼吸困难症状，进一步增强患者运动耐力水平，改善其肺功能，有助于提升生活质量。

关键词:

慢性阻塞性肺疾病, 中药封包, 肺康复训练, 呼吸困难症状, 运动耐力, 肺功能