国际医药卫生导报 ›› 2023, Vol. 29 ›› Issue (4): 484-487.DOI: 10.3760/cma.j.issn.1007-1245.2023.04.010

• 科研课题专栏 • 上一篇    下一篇

经皮椎体后凸成形术治疗骨质疏松性椎体骨折的临床疗效

陈政1  桑飞2  姜磊2  刘青柏2   

  1. 1南京医科大学附属淮安第一医院骨科,淮安 2230002南京医科大学康达学院附属涟水医院骨科,淮安 223400

  • 收稿日期:2022-10-18 出版日期:2023-03-15 发布日期:2023-03-05
  • 通讯作者: 刘青柏,Email:liu678vip@163.com
  • 基金资助:

    江苏省卫生健康委科研项目(Z2022042

Percutaneous kyphoplasty in treatment of osteoporotic vertebral fractures 

Chen Zheng1, Sang Fei2, Jiang Lei2, Liu Qingbai2   

  1. 1 Department of Orthopedics, Huan'an First Hospital, Nanjing Medical University, Huan'an 223000, China; 2 Department of Orthopedics, Lianshui Hospital, Kangda College, Nanjing Medical University, Huan'an 223400, China

  • Received:2022-10-18 Online:2023-03-15 Published:2023-03-05
  • Contact: Liu Qingbai, Email: liu678vip@163.com
  • Supported by:

     Scientific Research Project of Jiangsu Health Commission (Z2022042)

摘要:

目的 探讨经皮椎体后凸成形术(percutaneous kyphoplastyPKP)治疗骨质疏松性椎体骨折的临床疗效。方法 选择南京医科大学附属淮安第一医院20172月至20191月收治的骨质疏松性椎体骨折患者92例,随机数字表法分为试验组(46例)与常规组(46例)。试验组中男26例、女20例,年龄528067.25±8.25)岁,常规组中男25例、女21例,年龄538368.14±8.36)岁。常规组采用经皮椎体成形术治疗,试验组采用PKP治疗。比较两组患者的康复优良率、日本骨科协会(Japanese Orthopaedic AssociationJOA)评分及术后3个月内并发症发生情况。计量资料采用t检验、计数资料采用χ2检验、等级资料采用秩和检验。结果 治疗后,两组手术优良率等级分布比较,差异有统计学意义(Z=5.241P=0.021),且试验组的优良率[86.96%40/46)]高于常规组[67.39%31/46)],差异有统计学意义(χ2=4.998P=0.025)。术后两组JOA评分均高于术前,且试验组高于常规组[(25.25±3.14)分比(20.25±2.58)分],差异有统计学意义(t=8.334P<0.001)。术后3个月内,试验组并发症发生率为6.52%3/46),常规组并发症发生率为21.74%10/46),试验组术后3个月内并发症发生率低于常规组(χ2=4.389P=0.036)。结论 PKP治疗骨质疏松性椎体骨折,可提高患者的康复优良率,减轻腰痛,降低并发症发生率,值得推广应用。

关键词:

经皮椎体成形术, 经皮椎体后凸成形术, 骨质疏松性椎体骨折, 切口表面感染, 骨水泥渗漏

Abstract:

Objective To investigate the clinical efficacy of percutaneous kyphoplasty (PKP) in the treatment of osteoporotic vertebral fractures. Methods Ninety-two patients with osteoporotic vertebral fractures admitted to Huan'an First Hospital, Nanjing Medical University from February 2017 to January 2019 were divided into an experimental group and a conventional group by the random number table method, with 46 cases in each group. In the experimental group, there were 26 males and 20 females; they were 52-80 (67.25 ± 8.25) years old. In the conventional group, there were 25 males and 21 females; they were 53-83 (68.14 ± 8.36) years old. The conventional group were treated with percutaneous vertebroplasty, and the experimental group with PKP. The excellent and good rates of rehabilitation, scores of Japanese Orthopedic Association (JOA), and complications within 3 months after operation were compared between these two groups. t test was used for the measurement data, χ2 for the enumeration data, and rank-sum tests for ranked data. Results There was a statistical difference in the grade distribution of the excellent and good rate of surgery between the two groups after the treatment (Z=5.241, P=0.021); the excellent and good rate of the experimental group was higher than that of the conventional group [86.96% (40/46) vs. 67.39% (31/46); χ2=4.998, P=0.025]. The JOA score in the experimental group was higher than that in the conventional group after the operation [(25.25 ± 3.14) vs. (20.25 ± 2.58); t=8.334, P<0.001]. The incidence of complications within 3 months after the operation in the experimental group was lower than that in the conventional group [6.52% (3/46) vs. 21.74% (10/46); χ2=4.389, P=0.036]. Conclusion PKP in the treatment of patients with osteoporotic vertebral fractures can improve the excellent rate and reduce their low back pain and the incidence of complications, so it is worth being clinically generalized.

Key words:

Percutaneous vertebroplasty, Percutaneous kyphoplasty, Osteoporotic vertebral fractures, Incision surface infection, Bone cement leakage