阿帕替尼治疗消化道肿瘤致口腔黏膜炎的护理干预：5例病例报告

doi:10.3760/cma.j.issn.1007-1245.2022.01.033

国际医药卫生导报 ›› 2022, Vol. 28 ›› Issue (1): 128-131.DOI: 10.3760/cma.j.issn.1007-1245.2022.01.033

阿帕替尼治疗消化道肿瘤致口腔黏膜炎的护理干预：5例病例报告

李芬¹, 柯春连¹, 邓小红²

¹中山大学附属第三医院普外科，广州　510000； ²中山大学附属第三医院护理部，广州　510000

收稿日期:2021-08-05 出版日期:2022-01-01 发布日期:2022-02-01
通讯作者: 李芬，Email：770860563@qq.com

Nursing intervention of oral mucositis caused by apatinib for digestive tract tumors: a report of 5 cases

Li Fen¹, Ke Chunlian¹, Deng Xiaohong²

¹Department of General Surgery, Third Hospital, Sun Yat-sen University, Guangzhou 510000, China; ²Nursing Department, Third Hospital, Sun Yat-sen University, Guangzhou 510000, China

Received:2021-08-05 Online:2022-01-01 Published:2022-02-01
Contact: Li Fen，Email：770860563@qq.com

摘要/Abstract

摘要： 目的　总结应用阿帕替尼治疗消化道肿瘤致患者口腔黏膜炎的护理经验。方法　2020年6月至2021年6月中山大学附属第三医院岭南医院普外科5例消化道肿瘤患者（男3例，女2例，年龄43～56岁）使用阿帕替尼后，均出现了口腔黏膜炎，2例患者出现4度口腔黏膜炎；2例患者出现3度口腔黏膜炎；1例患者出现2度口腔黏膜炎。给予患者护理干预，包括综合化心理护理、严密用药指导、个性化饮食方案、全面的健康知识宣教等。结果　2例4度口腔黏膜炎患者疼痛程度迅速缓解，2 d后即可经口进食；5例患者3～5 d 临床症状均消失。结论　及时发现和评估患者的口腔黏膜炎的临床表现是关键，给予正规的治疗和综合化护理，缓解患者的疼痛症状，制定个性化饮食方案，关注患者的心理护理和健康宣教是护理要点。

关键词: 阿帕替尼, 口腔黏膜炎, 护理干预

Abstract: Objective　To summarize the nursing experience of patients with oral mucositis caused by apatinib for digestive tract tumors. Methods　From June 2020 to June 2021, 5 patients with digestive tract tumors, including 3 males and 2 females who were 43 to 56 years old, treated at Department of General Surgery, Lingnan Hospital, Third Hospital, Sun Yat-sen University developed oral mucositis after taking apatinib, including 2 cases of degree 4 oral mucositis, 2 cases of degree 3, and 1 case of degree 1. The patients were given nursing interventions, including comprehensive psychological care, strict medication guidance, personalized diet program, comprehensive health education, and so on. Results　The 2 cases of degree 4 had rapid relief of pain, and could eat by mouth after 2 days. All the 5 patients had no clinical symptoms after 3-5 days' care. Conclusions　Timely detection and evaluation of the clinical manifestations of patients with oral mucositis is the key. The nursing key points are formal treatment and comprehensive care, relieving their pain symptoms, developing personalized diet program, and paying attention to their psychological nursing and health education.

Key words: Apatinib, Oral mucositis, Nursing intervention

李芬, 柯春连, 邓小红. 阿帕替尼治疗消化道肿瘤致口腔黏膜炎的护理干预：5例病例报告[J]. 国际医药卫生导报, 2022, 28(1): 128-131.

Li Fen, Ke Chunlian, Deng Xiaohong. Nursing intervention of oral mucositis caused by apatinib for digestive tract tumors: a report of 5 cases[J]. International Medicine and Health Guidance News, 2022, 28(1): 128-131.

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阿帕替尼治疗消化道肿瘤致口腔黏膜炎的护理干预：5例病例报告

Nursing intervention of oral mucositis caused by apatinib for digestive tract tumors: a report of 5 cases

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