国际医药卫生导报 ›› 2022, Vol. 28 ›› Issue (8): 1162-1163.DOI: 10.3760/cma.j.issn.1007-1245.2022.08.030

• 病例报告 • 上一篇    下一篇

注射用头孢唑肟钠致癫痫1例并文献复习

崔红霞  王俊腾   

  1. 青岛大学附属威海市中心医院药学部,威海 264400
  • 收稿日期:2021-11-19 出版日期:2022-04-15 发布日期:2022-05-09
  • 通讯作者: 崔红霞,Email:40386@sohu.com

Epilepsy caused by ceftizoxime sodium: one case report and literature review 

Cui Hongxia, Wang Junteng   

  1. Department of Pharmacy, Weihai Central Hospital Affiliated to Qingdao University, Weihai 264400, China
  • Received:2021-11-19 Online:2022-04-15 Published:2022-05-09
  • Contact: Cui Hongxia, Email: 40386@sohu.com

摘要: 本文报道青岛大学附属威海市中心医院2021年10月1例慢性肾炎患者应用头孢唑肟发生药源性癫痫,通过Naranjo概率评分判断患者的癫痫发作极可能是头孢唑肟所致,并通过查阅文献探讨慢性肾功能不全患者应用头孢唑肟发生癫痫的机制,以期为临床治疗工作提供参考。

关键词: 头孢唑肟钠, 癫痫, 慢性肾炎

Abstract: In this paper, a case of chronic nephritis with drug-induced epilepsy induced by ceftizoxime in Weihai Central Hospital Affiliated to Qingdao University in October 2021 was reported. Naranjo probability score was used to determine that the patient's epilepsy was most likely caused by ceftizoxime. The mechanism of ceftizoxime-induced epilepsy in patients with chronic renal insufficiency was discussed through literature review, in order to provide reference for clinical treatment.

Key words: Ceftizoxime sodium, Epilepsy, Chronic nephritis