国际医药卫生导报 ›› 2025, Vol. 31 ›› Issue (19): 3240-3245.DOI: 10.3760/cma.j.cn441417-20250509-19015

• 论著 • 上一篇    下一篇

CO2激光联合凯格尔运动在不同年龄女性压力性尿失禁治疗中的效果

杨栋清1  包莉艳1  阴丽莹1  陈建国2   

  1. Yang Dongqing1, Bao Liyan1, Yin Liying1, Chen Jianguo2

  • 收稿日期:2025-05-09 出版日期:2025-10-01 发布日期:2025-10-24
  • 通讯作者: 陈建国,Email:776482839@qq.com
  • 基金资助:

    2022年珠海市社会发展领域科技计划(222000400116)

The effect of CO2 laser combined with Kegel exercises in the treatment of stress urinary incontinence in women of different ages

Yang Dongqing1, Bao Liyan1, Yin Liying1, Chen Jianguo2   

  1. 1 Department of Obstetrics and Gynecology, Zhuhai Doumen District Maternal and Child Health Hospital, Zhuhai 519100, China; 2 Department of Gynecology, Guangdong Provincial People's Hospital, Guangzhou 510000, China

  • Received:2025-05-09 Online:2025-10-01 Published:2025-10-24
  • Contact: Chen Jianguo, Email: 776482839@qq.com
  • Supported by:

    2022 Social Development Field Science and Technology Plan of Zhuhai City (222000400116)

摘要:

目的 探讨CO2激光联合凯格尔运动治疗不同年龄层压力性尿失禁患者的临床效果及其对生活质量的影响。方法 选取2023年2月至2024年10月在珠海市斗门区妇幼保健院妇产科就诊的100例女性压力性尿失禁患者作为研究对象。按年龄分为育龄期患者(<45岁)和围绝经后期患者(≥45岁),各50例;分层后再随机分为对照组和研究组,各25例。育龄期患者:对照组年龄(35.72±4.82)岁,体重指数(22.06±0.87)kg/m2,轻度压力性尿失禁8例,中度压力性尿失禁17例;研究组年龄(36.60±4.20)岁,体重指数(21.72±1.04)kg/m2,轻度压力性尿失禁14例,中度压力性尿失禁11例。围绝经后期患者:对照组年龄(54.88±6.19)岁,体重指数(21.85±0.75)kg/m2,轻度压力性尿失禁9例,中度压力性尿失禁16例;研究组年龄(53.44±8.80)岁,体重指数(22.09±0.73)kg/m2,轻度压力性尿失禁8例,中度压力性尿失禁17例。对照组采用凯格尔运动治疗,研究组采用CO2激光联合凯格尔运动治疗,均连续治疗1疗程(3个月)。比较各组育龄期、围绝经后期患者治疗前后1 h漏尿量(1 h尿垫试验)、压力性尿失禁症状评分[国际尿失禁咨询委员会尿失禁问卷表简表(ICI-Q-SF)]、生活质量[世界卫生组织生存质量测定量表简表(WHOQOL-BREF)]、焦虑程度[焦虑自评量表(SAS)]。采用独立样本t检验、配对t检验和χ2检验进行统计学分析。结果 治疗后,研究组育龄期、围绝经后期患者1 h漏尿量和ICI-Q-SF评分均低于对照组[(0.56±0.27)g比(1.26±1.24)g、(4.52±3.06)分比(6.40±2.94)分;(0.68±0.26)g比(5.46±1.02)g、(7.52±3.95)分比(11.24±4.53)分](均P<0.05);研究组育龄期、围绝经后期患者WHOQOL-BREF评分均高于对照组[(86.44±4.39)分比(77.76±4.44)分;(86.12±5.06)分比(60.80±4.92)分](均P<0.05);两组育龄期、围绝经后期患者SAS评分比较,差异均无统计学意义(均P>0.05)。结论 单纯凯格尔运动对于育龄期患者疗效良好,但对于围绝经后期患者疗效欠佳。此外,在育龄期和围绝经后期患者中,CO2激光与凯格尔运动联合治疗压力性尿失禁疗效确切,可改善患者生活质量,缓解焦虑情绪。

关键词:

压力性尿失禁, 盆底肌训练, CO2激光, 凯格尔运动, 焦虑

Abstract:

Objective To explore the clinical efficacy of CO2 laser combined with Kegel exercises in treating patients with stress urinary incontinence of different age groups and its impact on quality of life. Methods A total of 100 female patients with stress urinary incontinence who visited the obstetrics and gynecology department of Zhuhai Doumen District Maternal and Child Health Hospital from February 2023 to October 2024 were selected as the study subjects. The patients were divided by age into the reproductive age group (<45 years old) and the perimenopausal group (≥45 years old), with 50 cases in each group. After stratification, they were randomly divided into the control group and the study group, with 25 cases in each group. Reproductive age patients: in the control group, the age was (35.72±4.82) years, the body mass index was (22.06±0.87) kg/m2, and there were 8 cases of mild stress urinary incontinence and 17 cases of moderate stress urinary incontinence; in the study group, the age was (36.60±4.20) years, the body mass index was (21.72±1.04) kg/m2, and there were 14 cases of mild stress urinary incontinence and 11 cases of moderate stress urinary incontinence. Perimenopausal patients: in the control group, the age was (54.88±6.19) years, the body mass index was (21.85±0.75) kg/m2, and there were 9 cases of mild stress urinary incontinence and 16 cases of moderate stress urinary incontinence; in the study group, the age was (53.44±8.80) years, the body mass index was (22.09±0.73) kg/m2, and there were 8 cases of mild stress urinary incontinence and 17 cases of moderate stress urinary incontinence. The control group received Kegel exercise therapy, while the study group received CO2 laser therapy combined with Kegel exercise. All groups received a continuous treatment course (3 months). The 1-hour urine leakage volume (1-hour urine pad test) were compared before and after treatment in each group of reproductive-aged and post-menopausal patients, as well as the symptoms score of stress urinary incontinence [International Consultation on Incontinence Questionnaire - Short Form (ICI-Q-SF)], quality of life [World Health Organization Quality of Life - Brief Version (WHOQOL-BREF)], and anxiety level [Self-Rating Anxiety Scale (SAS)]. Independent sample t test, paired t test, and χ2 test were used for statistical analysis. Results After treatment, the 1-hour urine leakage volume and ICI-Q-SF score of the reproductive age and perimenopausal patients in the study group were lower than those in the control group [(0.56±0.27) g vs. (1.26±1.24) g, (4.52±3.06) points vs. (6.40±2.94) points; (0.68±0.26) g vs. (5.46±1.02) g, (7.52±3.95) points vs. (11.24±4.53) points] (all P<0.05); the WHOQOL-BREF scores of the reproductive age and perimenopausal patients in the study group were higher than those in the control group [(86.44±4.39) points vs. (77.76±4.44) points; (86.12±5.06) points vs. (60.80±4.92) points] (both P<0.05). There was no statistically significant difference in the SAS scores between the two groups of patients of reproductive age and those in the perimenopausal (both P>0.05). Conclusions Simple Kegel exercises are highly effective for patients in the reproductive age group, but have less effect on those in the perimenopausal. Moreover, in both the reproductive age group and the perimenopausal group, the combined treatment of CO2 laser and Kegel exercises for stress urinary incontinence is highly effective, which can improve the quality of life of patients and alleviate their anxiety.

Key words:

Stress urinary incontinence, Pelvic floor muscle training, CO2 , laser, Kegel exercises, Anxiety