关键词: 腹膜透析, 规律性随访, 并发症

Abstract: Objective　To study the correlation between regular follow-up and complications in peritoneal dialysis patients, and to provide basis for clinical diagnosis and treatment and patient management. Methods　A single-center retrospective analysis method was used. The data of 212 peritoneal dialysis patients who were followed up in Huadu District People's Hospital of Guangzhou from January to October 2020 were collected. Among them, 156 patients themselves were followed up once a month, as a regular follow-up group, and other 56 patients with poor regular follow-up as an irregular follow-up group. The basic and clinical data of the two groups were analyzed. χ² test was used for the count data, independent sample t test or Wilcoxon rank sum test was used for the measurement data, and Spearman rank correlation analysis was used for correlation analysis. Results　In the irregular follow-up group, the time of dialysis was 44.50 (22.00, 77.50) months, the education level above middle school accounted for 53.57% (30/56), the systolic blood pressure was (147.84±19.79) mmHg (1 mmHg=0.133 kPa), the incidence of cardiovascular events was 28.57% (16/56), and the incidence of respiratory diseases was 10.71% (6/56), which were higher than those in the regular follow-up group (all P<0.05). In the irregular follow-up group, the complete self-care accounted for 73.21% (41/56), the fluid change by patients themselves accounted for 71.43% (40/56), the residual urine volume was 100.00 (0.00, 300.00) ml, and the serum albumin level was (33.65±5.14) g/L, which were lower than those in the regular follow-up group (all P<0.05). The 56 patients in the irregular follow-up group had 53 cases of complications, accounting for 94.64% (53/56); among the causes of complications, cardiovascular events accounted for 26.32% (35/133). Correlation analysis showed that regular follow-up was negatively correlated with self-care ability, fluid change operators, time of dialysis, systolic blood pressure, cardiovascular events, respiratory disease, and other diseases (r=-0.176, -0.272, -0.167, -0.196, -0.195, -0.218, -0.159; P=0.011, 0.001, 0.015, 0.004, 0.004, 0.001, 0.021); regular follow-up was positively correlated with education level, residual urine volume, and serum albumin level (r=0.141, 0.204, 0.165; P=0.041, 0.003, 0.016). Conclusion　During the long-term maintenance peritoneal dialysis treatment, it is of great significance to strengthen the regular follow-up for patients to reduce complications, especially the occurrence of cardiovascular and cerebrovascular events.

Key words: Peritoneal dialysis, Regular follow-up, Complications