国际医药卫生导报 ›› 2024, Vol. 30 ›› Issue (4): 638-640.DOI: 10.3760/cma.j.issn.1007-1245.2024.04.025

• 病例报告 • 上一篇    下一篇

干细胞治疗肝硬化合并银屑病患者1例报道及文献复习

王凤梅  张文华  陈多兆  白兆娟   

  1. 甘肃省武威肿瘤医院肝病科,武威 733000

  • 收稿日期:2023-10-19 出版日期:2024-02-01 发布日期:2024-03-07
  • 通讯作者: 王凤梅,Email:wangfm1304@163.com
  • 基金资助:

    武威市科技局科技计划项目(ww2001010、ww2101113)

Stem cell therapy for a patient with cirrhosis and psoriasis: a case report and literature review

Wang Fengmei, Zhang Wenhua, Chen Duozhao, Bai Zhaojuan   

  1. Department of Hepatology, Gansu Wuwei Tumour Hospital, Wuwei 733000, China

  • Received:2023-10-19 Online:2024-02-01 Published:2024-03-07
  • Contact: Wang Fengmei ,Email: wangfm1304@163.com
  • Supported by:

    Science and Technology Plan Project of Wuwei Science and Technology Bureau (ww2001010, ww2101113)

摘要:

银屑病是一种慢性、复发性疾病。临床表现为鳞屑性红斑或斑块,呈局限或广泛分布,病情反复,严重影响患者生活质量。乙型肝炎肝硬化失代偿期可能出现多种并发症,如腹水、消化道出血等。间充质干细胞(mesenchymal stem cells,MSCs)是一种多能非造血基质细胞,存在于不同的身体组织中。近年来,MSCs被尝试应用于肝硬化失代偿期以及银屑病的患者中,部分患者取得了较好的效果。本例乙肝肝硬化失代偿期合并银屑病患者,应用干细胞治疗取得了较好的疗效,为此类患者的治疗提供了一定的参考价值。

关键词:

银屑病, 肝硬化, 失代偿期, 干细胞治疗

Abstract:

Psoriasis is a chronic, recurrent disease characterized by squamous erythema or plaques, which are localized or widely distributed. The condition is recurrent and seriously affects patients' quality of life. During the decompensated phase of hepatitis B cirrhosis, various complications may occur, such as ascites and gastrointestinal bleeding. Mesenchymal stem cells (MSCs) are pluripotent non hematopoietic stromal cells that exist in different body tissues. In recent years, they have been attempted to be applied in patients with decompensated liver cirrhosis and psoriasis, and some patients have achieved good results. In this paper, a patient with decompensated liver cirrhosis and psoriasis was treated by stem cell therapy, and he achieved good results, which provided a certain reference value for the treatment of such patients.

Key words:

Psoriasis, Liver cirrhosis, Decompensated phase, Stem cell therapy