关键词: 胸膜固定术, 碘伏, 氩气刀, 内科胸腔镜, 胸腔积液

Abstract: Objective To observe the efficacy and safety of argon knife combined with iodophor pleurodesis by medical thoracoscopy in the treatment of malignant pleural effusion. Methods A total of 54 patients with malignant pleural effusion who were hospitalized in Department of Respiratory and Critical Care Medicine of our hospital from October 2017 to May 2020 were retrospectively analyzed. Among them, 18 patients underwent argon knife combined with iodophor pleurodesis by medical thoracoscopy (observation group), and 36 patients underwent cis-platinum pleurodesis after thoracic closed drainage (control group). The efficiency and safety of the two groups were compared. Results The total effective rates of the observation group and the control group were 94.44% (17/18) and 52.78% (19/36), with statistically significant difference (P<0.01). The adverse reactions rates of the observation group and the control group were 50.00% (9/18) and 41.67% (15/36), without statistically significant difference (P>0.05). Conclusion Argon knife combined with iodophor pleurodesis by medical thoracoscopy has the advantages of high curative effect, high safety, and less adverse reactions in the treatment of malignant pleural effusion, which is worthy of clinical promotion.

Key words: Pleurodesis, Iodophor, Argon knife, Medical thoracoscopy, Pleural effusion