圈套器冷切除术治疗结直肠息肉患者的效果

doi:10.3760/cma.j.cn441417-20241014-16025

国际医药卫生导报 ›› 2025, Vol. 31 ›› Issue (16): 2766-2769.DOI: 10.3760/cma.j.cn441417-20241014-16025

圈套器冷切除术治疗结直肠息肉患者的效果

曹雅程相超赵锦华刘耀刚涂成志丁圣

河南省直第三人民医院消化病诊疗中心，郑州 450000

收稿日期:2024-10-14 出版日期:2025-08-15 发布日期:2025-08-28
通讯作者: 程相超，Email：553204613@qq.com
基金资助:
2023年度河南省医学科技攻关计划联合共建项目（LHGJ20230668）；河南省慈善联合总会·道健基金科研项目（szsyky24006）；河南省慈善联合总会·道健基金科研项目（豫慈基金20180716025号）

Effect of cold snare polypectomy for patients with colorectal polyps

Cao Ya, Cheng Xiangchao, Zhao Jinhua, Liu Yaogang, Tu Chengzhi, Ding Sheng

Digestive Disease Diagnosis and Treatment Center, The Third People's Hospital of Henan Province, Zhengzhou 450000, China

Received:2024-10-14 Online:2025-08-15 Published:2025-08-28
Contact: Cheng Xiangchao, Email: 553204613@qq.com
Supported by:
Co-construction Project of Problem-tackling Plan of Medical Science and Technology in Henan in 2023 (LHGJ20230668); Henan Charity General Federation·Scientific Research Project of Daojian Fund (szsyky24006); Henan Charity General Federation·Scientific Research Project of Daojian Fund (No.20180716025)

摘要/Abstract

摘要：

目的　探讨圈套器冷切除术治疗结直肠息肉患者的效果。方法　选取2023年6月至2024年8月河南省直第三人民医院收治的148例结直肠息肉患者为研究对象。根据手术方法将其分为对照组（内镜下黏膜切除术治疗）和研究组（圈套器冷切除术治疗），各74例。对照组男47例，女27例，年龄（50.02±5.87）岁，息肉长径（6.43±1.25）mm。研究组男48例，女26例，年龄（49.87±6.32）岁，息肉长径（6.52±1.18）mm。比较两组手术相关指标、手术前后血清疼痛因子、应激反应指标、并发症发生情况。采用χ²检验、t检验进行统计分析。结果　研究组息肉切除时间、住院时间均短于对照组（t=12.893、9.473，均P<0.05）。两组息肉完整切除率差异无统计学意义（χ²=0.600，P>0.05）。术后1 d，两组血清疼痛因子水平均高于术前，但研究组上述指标水平均低于对照组（t=10.079、12.097，均P<0.05）。术后1 d，两组肾上腺素、皮质醇、去甲肾上腺素水平均高于术前，但研究组上述指标水平均低于对照组［（240.03±26.14）pmol/L比（269.41±25.56）pmol/L、（134.26±12.78）μg/L比（160.05±13.29）μg/L、（2.41±0.32）nmol/L比（3.59±0.27）nmol/L］（t=6.913、12.033、24.244，均P<0.05）。研究组并发症总发生率低于对照组（χ²=12.397，P<0.05）。结论　圈套器冷切除术治疗结直肠息肉患者可缩短息肉切除时间、住院时间，减轻疼痛程度与应激反应程度，且安全性较高。

关键词:

结直肠息肉, 圈套器冷切除术, 内镜下黏膜切除术, 应激指标

Abstract:

Objective　To explore the effect of cold snare polypectomy for patients with colorectal polyps. Methods　One hundred and forty-eight patients with colorectal polyps treated at the Third People's Hospital of Henan Province from June 2023 to August 2024 were selected as the study objects. The patients were divided into a control group, treated with endoscopic mucosal resection, and a study group, treated with cold snare polypectomy, according to the surgical methods, with 74 cases in each group. In the control group, there were 47 males and 27 females; they were (50.02±5.87) years old; the maximum diameter of the polyp was (6.43±1.25) mm. In the study group, there were 48 males and 26 females; they were (49.87±6.32) years old; the maximum diameter of the polyp was (6.52±1.18) mm. The surgery-related indicators, serum pain factors, stress response indicators, occurrence of complications were compared between the two groups. χ² and t tests were used for the statistical analysis. Results　The polyp resection time and hospital stay in the study group were shorter than those in the control group (t=12.893 and 9.473; both P<0.05). There was no statistical difference in the complete polyp resection rate between the two groups (χ²=0.600; P>0.05). One day after the operation, the serum levels of pain factors were higher than those before the operation in both groups, but the levels in the study group were lower than those in the control group (t=10.079 and 12.097; both P<0.05). One day after the operation, the levels of adrenaline, cortisol, and norepinephrine were higher than those before the operation in both groups, but the levels in the study group were lower than those in the control group [(240.03±26.14) pmol/L vs. (269.41±25.56) pmol/L, (134.26±12.78) μg/L vs. (160.05±13.29) μg/L and (2.41±0.32) nmol/L vs. (3.59±0.27) nmol/L] (t=6.913, 12.033, and 24.244; all P<0.05). The total incidence rate of complications in the study group was lower than that in the control group (χ²=12.397; P<0.05). Conclusion　Cold snare polypectomy in the treatment of patients with colorectal polyps can shorten their polyp resection time and hospital stay, and reduce their pain and stress response, with high safety.

Key words:

Colorectal polyps, Cold snare polypectomy, Endoscopic mucosal resection, Stress indicators

曹雅程相超赵锦华刘耀刚涂成志丁圣.

圈套器冷切除术治疗结直肠息肉患者的效果 [J]. 国际医药卫生导报, 2025, 31(16): 2766-2769.

Cao Ya, Cheng Xiangchao, Zhao Jinhua, Liu Yaogang, Tu Chengzhi, Ding Sheng.

Effect of cold snare polypectomy for patients with colorectal polyps [J]. International Medicine and Health Guidance News, 2025, 31(16): 2766-2769.

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圈套器冷切除术治疗结直肠息肉患者的效果

Effect of cold snare polypectomy for patients with colorectal polyps

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