原发性乳腺血管肉瘤合并卵巢血管肉瘤的超声诊断1例并文献复习

doi:10.3760/cma.j.cn441417-20240507-08004

国际医药卫生导报 ›› 2025, Vol. 31 ›› Issue (8): 1250-1253.DOI: 10.3760/cma.j.cn441417-20240507-08004

原发性乳腺血管肉瘤合并卵巢血管肉瘤的超声诊断1例并文献复习

何苑洵张凌烟黄君

暨南大学附属第一医院超声科，广州 510632

收稿日期:2024-05-07 出版日期:2025-04-15 发布日期:2025-04-20
通讯作者: 黄君，Email：tzhuoyumin@126.com
基金资助:
广东省医学科学技术研究基金（B2023321）

Ultrasound in diagnosis of primary breast angiosarcoma complicated with ovarian angiosarcoma in 1 case and literature review

He Yuanxun, Zhang Lingyan, Huang Jun

Department of Ultrasound, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China

Received:2024-05-07 Online:2025-04-15 Published:2025-04-20
Contact: Huang Jun, Email: tzhuoyumin@126.com
Supported by:
Guangdong Medical Science and Technology Research Fund (B2023321)

摘要/Abstract

摘要：

原发性乳腺血管肉瘤（primary breast angiosarcoma，PBA）及卵巢血管肉瘤均为罕见的、具有高度侵袭性和转移潜力的肿瘤，临床上同时罹患以上两种肿瘤的病例极为罕见。以上两种肿瘤在临床上均无明显特征性表现，容易发生漏诊、误诊。为帮助临床医生早期诊断此病，现回顾性分析2023年8月收入暨南大学附属第一医院的经手术病理证实的1例PBA患者的临床资料及超声表现。该患者术后4个月经阴道超声发现左侧卵巢肿物，术后病理提示为成熟囊性畸胎瘤合并血管肉瘤。本文亦提及卵巢血管肉瘤的二维超声图像及彩色多普勒超声图像特点，并结合文献进行总结、归纳。

关键词:

血管肉瘤, 乳腺肿瘤, 卵巢肿瘤, 超声检查, 病理, 治疗

Abstract:

Primary breast angiosarcoma (PBA) and ovarian angiosarcoma are rare tumors with high aggressive and metastatic potential, and clinical cases of both tumors at the same time are rare. In order to help clinicians diagnose this disease early, the clinical data and ultrasound manifestations of a patient with PBA confirmed by surgical pathology who was admitted to The First Affiliated Hospital of Jinan University in August 2023 were mainly retrospectively analyzed, and the left ovarian mass was found by transvaginal ultrasound 4 months after surgery. The postoperative pathology showed that the patient had mature cystic teratoma and angiosarcoma. The characteristics of two-dimensional ultrasound images and color Doppler ultrasound images of ovarian angiosarcoma are also mentioned in this article, and summarized in conjunction with the literature.

Key words:

Angiosarcoma, Breast neoplasms, Ovarian neoplasms, Ultrasound, Pathology, Therapy

何苑洵张凌烟黄君.

原发性乳腺血管肉瘤合并卵巢血管肉瘤的超声诊断1例并文献复习 [J]. 国际医药卫生导报, 2025, 31(8): 1250-1253.

He Yuanxun, Zhang Lingyan, Huang Jun.

Ultrasound in diagnosis of primary breast angiosarcoma complicated with ovarian angiosarcoma in 1 case and literature review [J]. International Medicine and Health Guidance News, 2025, 31(8): 1250-1253.

参考文献

[1] Darre T, Djiwa T, N'Timon B, et al. Breast primary angiosarcoma: a clinicopathologic and imaging study of a series cases [J]. Breast Cancer (Auckl), 2022, 16: 11782234221086726. DOI: 10.1177/11782234221086726.
[2] Ichiki T, Yamada Y, Ito T, et al. Histological and immunohistochemical prognostic factors of primary angiosarcoma [J]. Virchows Arch, 2023, 483(1): 59-69. DOI: 10.1007/s00428-023-03572-z.
[3] 郭炳君,李凡. 原发性乳腺血管肉瘤的超声诊断[J]. 中国超声医学杂志,2023,39(4):456-458. DOI:10.3969/j.issn.1002-0101.2023.04.028.
[4] Naeem M, Zulfiqar M, Ballard DH, et al. "The unusual suspects"-mammographic, sonographic, and histopathologic appearance of atypical breast masses [J]. Clin Imaging, 2020, 66: 111-120. DOI: 10.1016/j.clinimag.2020.04.039.
[5] El Khoudary SR, Aggarwal B, Beckie TM, et al. Menopause transition and cardiovascular disease risk: implications for timing of early prevention: a scientific statement from the American Heart Association [J]. Circulation, 2020, 142(25): e506-e532. DOI: 10.1161/CIR.0000000000000912.
[6] 李响,王学梅,耿晶. 年轻乳腺血管肉瘤的超声与病理对照分析1例[J]. 中国临床医学影像杂志,2012,23(1):71-72. DOI:10.3969/j.issn.1008-1062.2012.01.030.
[7] Yang OO, Lan T, He JL, et al. Magnetic resonance imaging and contrast-enhanced ultrasound findings of a recurrent primary breast angiosarcoma: a case report [J]. Medicine (Baltimore), 2021, 100(5): e24625. DOI: 10.1097/MD.0000000000024625.
[8] 李秀明,刘福兴. 乳腺超声造影与彩色多普勒超声在乳腺肿瘤诊断中的应用及准确性分析[J]. 影像研究与医学应用,2024,8(15):110-112,115. DOI:10.3969/j.issn.2096-3807.2024.15.034.
[9] 韩鄂辉,吕志红,洪玮,等. 乳腺血管肉瘤的超声造影表现1例[J]. 中国临床医学影像杂志,2014,25(7):527-528. DOI:10.3969/j.issn.1008-1062.2014.07.025.
[10] Liu X, Zheng S, Li Y, et al. Use of extended field-of-view ultrasound imaging in giant primary breast angiosarcoma: a case description [J]. Quant Imaging Med Surg, 2022, 12(1): 868-873. DOI: 10.21037/qims-21-280.
[11] Qin X, Wu Y, Yu L, et al. Metastasis of primary breast angiosarcoma to axillary and supraclavicular lymph nodes: a rare case diagnosed using imaging data [J]. J Int Med Res, 2021, 49(3): 3000605211002337. DOI: 10.1177/03000605211002337.
[12] Wang XY, Jakowski J, Tawfik OW, et al. Angiosarcoma of the breast: a clinicopathologic analysis of cases from the last 10 years [J]. Ann Diagn Pathol, 2009, 13(3): 147-150. DOI: 10.1016/j.anndiagpath.2009.02.001.
[13] 于江飞,沈滨. 乳腺血管肉瘤的临床研究进展[J]. 现代肿瘤医学,2024,32(1):178-181. DOI:10.3969/j.issn.1672-4992.2024.01.034.
[14] Issar PMR, Dewangan M, Issar AK. Primary angiosarcoma of the breast: a rare case report in postmenopausal women [J]. Indian J Radiol Imaging, 2022, 32(4): 607-610. DOI: 10.1055/s-0042-1754358.
[15] Baker GM, Schnitt SJ. Vascular lesions of the breast [J]. Semin Diagn Pathol, 2017, 34(5): 410-419. DOI: 10.1053/j.semdp.2017.05.013.
[16] Vohra LM, Jabeen D, Idrees R. Primary angiosarcoma of breast in an octogenarian woman: a case report with literature review [J]. Int J Surg Case Rep, 2023, 107: 108163. DOI: 10.1016/j.ijscr.2023.108163.
[17] Kudela E, Nachajova M, Biringer K, et al. Bilateral ovarian angiosarcoma arising from the mature cystic teratomas - a case report and review of the literature [J]. Int J Surg Case Rep, 2018, 42: 90-93. DOI: 10.1016/j.ijscr.2017.11.064.
[18] 李莹莹,李小华,门楠,等. 卵巢成熟性囊性畸胎瘤恶变为血管肉瘤1例并文献复习[J]. 诊断病理学杂志,2024,31(8):765-767. DOI:10.3969/j.jssn.1007-8096.2024.08.013.
[19] 李正金,张石云,潘云,等. 卵巢转移性血管肉瘤1例报道并文献复习[J]. 临床与实验病理学杂志,2009,25(2):197-198. DOI:10.3969/j.issn.1001-7399.2009.02.022.
[20] Takahashi H, Chaopotong P, Kajita S, et al. Mixed angiosarcoma, clear cell adenocarcinoma and mature teratoma elements in an ovarian tumor: a case report and literature review [J]. Pathol Int, 2012, 62(8): 538-542. DOI: 10.1111/j.1440-1827.2012.02831.x.
[21] 迪娜·海沙尔,陈放,潘欣芳,等. 原发性卵巢血管肉瘤1例报道并文献复习[J]. 中国医科大学学报,2023,52(3):273-277. DOI:10.12007/j.issn.0258-4646.2023.03.015.
[22] Iljazović E, Tomić S, Mustedanagić-Mujanović J, et al. Angiosarcoma of the ovary in an 11 year old girl: case report and review of the literature [J]. Bosn J Basic Med Sci, 2011, 11(2): 132-136. DOI: 10.17305/bjbms.2011.2599.
[23] An R, Men XJ, Ni XH, et al. Angiosarcoma of the breast: a review [J]. Heliyon, 2024, 10(3): e24413. DOI: 10.1016/j.heliyon.2024.e24413.
[24] Salminen SH, Wiklund T, Sampo MM, et al. Treatment and prognosis of radiation-associated breast angiosarcoma in a nationwide population [J]. Ann Surg Oncol, 2020, 27(4): 1002-1010. DOI: 10.1245/s10434-019-08085-1.
[25] Dogan A, Kern P, Schultheis B, et al. Radiogenic angiosarcoma of the breast: case report and systematic review of the literature [J]. BMC Cancer, 2018, 18(1): 463. DOI: 10.1186/s12885-018-4369-7.

原发性乳腺血管肉瘤合并卵巢血管肉瘤的超声诊断1例并文献复习

Ultrasound in diagnosis of primary breast angiosarcoma complicated with ovarian angiosarcoma in 1 case and literature review

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