Recent progress of adjuvants to local anesthetics in peripheral nerve
block

doi:10.3760/cma.j.issn.1007-1245.2022.23.024

Abstract

Abstract: Peripheral nerve block (PNB) is commonly used in surgical anesthesia and pain treatment. The length of analgesia when a single local anesthetic is used may not last long enough to satisfy clinical need. Adding adjuvants, such as opioids, α-2 agonist, steroids, and so on, may prolong analgesic effect. It is important to acquaintance the action mechanism, advantages, and limitations of these adjuvants to make better clinical choices in PNB.

Key words: Peripheral nerve block, Anesthesia, Local anesthetics, Adjuvants

摘要： 周围神经阻滞（PNB）是临床麻醉和疼痛治疗中常用的方法。单独用局麻药实施PNB，其镇痛维持时间常常难以满足临床需求。临床上通过应用辅助剂复合局麻药可改善镇痛效果，比较常用的有阿片类、α-2肾上腺素能受体激动剂、类固醇等。在应用这些辅助剂时，必须对其作用机制、临床应用优势及局限性等有足够的了解，以便在PNB应用时做出更佳的选择。

关键词: 周围神经阻滞, 镇痛, 局麻药, 辅助剂

Pan Zhihao, Yu Kaihua, Wang Bo, Ju Yanxin. Recent progress of adjuvants to local anesthetics in peripheral nerve block[J]. International Medicine and Health Guidance News, 2022, 28(23): 3355-.

潘志豪于凯华王波鞠衍馨. 辅助剂复合局麻药行周围神经阻滞的应用及发展趋势[J]. 国际医药卫生导报, 2022, 28(23): 3355-.

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Recent progress of adjuvants to local anesthetics in peripheral nerve block

辅助剂复合局麻药行周围神经阻滞的应用及发展趋势

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