Abstract:

Objective　To observe the effect of hyaluronic acid gel combined with Nd:YAG laser on tooth root sensitivity after periodental non-surgical treatment in the elderly. Methods　A total of 145 elderly patients receiving periodental non-surgical treatment in Shangqiu Hospital of Traditional Chinese Medicine from January 2021 to February 2022 were selected. According to different intervention methods, they were divided into a combined group (72 cases) and a laser group (73 cases). There were 45 males and 27 females in the combined group, with an age of (72.50±5.35) years old; there were 47 males and 26 females in the laser group, with an age of (71.50±5.34) years old. The laser group was treated with Nd:YAG laser, and the combined group was treated with hyaluronic acid gel on the basis. The number of oral bacteria, improvement of periodontal indexes, levels of serum inflammatory factors, and incidence of complications were compared between the two groups after treatment. t test and Chi-square test were used. Results　After treatment, the infection rates of bacteroides forsythus, porphyromonas gingivalis, and actinobacillus concomitatus were 5.56% (4/72), 4.16% (3/72), and 6.94% (5/72) in the combined group, which were significantly lower than 21.92% (16/73), 17.81% (13/73), and 20.55% (15/73) in the laser group, with statistically significant differences between the two groups (all P<0.05). The improvement degrees of plaque index, gingival bleeding index, periodontal probing depth, and attachment level in the combined group were significantly better than those in the laser group (all P<0.05). The levels of C-reactive protein, vascular endothelial growth factor, and interleukin-21, 35, and 1β in the combined group were significantly lower than those in the laser group (all P<0.05). The total incidence of complications in the combined group was 2.78% (2/72), which was significantly lower than 27.40% (20/73) in the laser group, with a statistically significant difference (χ²=14.998, P<0.001). Conclusion　For elderly patients receiving periodental non-surgical treatment, hyaluronic acid gel combined with Nd:YAG therapy can effectively improve their oral environment and periodontal indicators, helps to reduce the activities of inflammatory factors, and avoids a large number of complications during the treatment process, which is beneficial to improve their treatment experience and quality of life.

Key words: Hyaluronic acid gel, Nd:YAG laser, Periodental non-surgical treatment, Tooth root sensitivity, Oral pathogens

摘要： 目的　观察透明质酸凝胶联合Nd：YAG激光对老年患者牙周基础治疗后牙根敏感并发症的效果。方法　选取商丘市中医院2021年1月至2022年2月期间收治的145例老年牙周基础治疗患者，按照干预方式的不同，将其分为联合组（72例）和激光组（73例）。联合组男45例，女27例，年龄（72.50±5.35）岁；激光组男47例，女26例，年龄（71.50±5.34）岁。激光组采取Nd：YAG激光治疗，联合组在该治疗基础上增加透明质酸凝胶。对比两组患者治疗后的口腔病菌数量、牙周指标改善情况、各项血清炎性因子水平以及并发症发生情况。统计学方法采用t检验、χ²检验。结果　治疗后，联合组患者的福赛类杆菌、牙龈卟啉单胞菌和伴放线杆菌感染率分别为5.56%（4/72）、4.16%（3/72）、6.94%（5/72），均明显少于激光组患者的21.92%（16/73）、17.81%（13/73）、20.55%（15/73），两组比较差异均有统计学意义（均P<0.05）；联合组患者的菌斑指数、牙龈出血指数、牙周探诊深度和附着水平改善程度均明显优于激光组患者（均P<0.05）；联合组患者的C反应蛋白、血管内皮生长因子和白细胞介素-21、35以及1β水平均明显低于激光组患者（均P<0.05）；联合组患者的并发症总发生率为2.78%（2/72），明显低于激光组患者的27.40%（20/73），两组比较差异有统计学意义（χ²=14.998，P<0.001）。结论　对老年牙周基础治疗患者采取透明质酸凝胶联合Nd：YAG疗法，可以有效地改善患者的口腔环境、牙周指标，帮助其降低炎性因子活动水平，能够避免其在治疗过程中出现大幅度的并发症，有利于提高其治疗体验和生活质量。

关键词: 透明质酸凝胶, Nd：YAG激光, 牙周基础治疗, 牙根敏感, 口腔病原菌