Clinical efficacy of vertebroplasty and pedicle screw fixation combined with microwave ablation in the treatment of spinal metastases

doi:10.3760/cma.j.cn441417-20250217-15015

Abstract

Abstract:

Objective　To investigate the clinical efficacy of vertebroplasty and pedicle screw fixation combined with microwave ablation in the treatment of spinal metastases. Methods　A retrospective analysis was conducted on the clinical data of 80 patients with spinal metastases who were admitted to Honghui Hospital Affiliated to Xi'an Jiaotong University from January 2022 to December 2023. The patients were divided into a control group (38 cases) and an observation group (42 cases) based on the different surgical methods. In the control group, there were 25 males and 13 females, with an age of (64.78±7.90) years old and a disease duration of (5.32±1.60) months; in the observation group, there were 28 males and 14 females, with an age of (65.71±9.55) years old and a disease duration of (5.51±1.24) months. The control group was treated with percutaneous vertebroplasty, and the observation group was treated with vertebroplasty and pedicle screw fixation combined with microwave ablation. The general data, perioperative indicators, follow-up results, and postoperative complications of the two groups were statistically analyzed. Statistical analysis was conducted using independent sample t test and χ² test. Results　The operation time [(125.69±16.48) minutes], ambulation time [(1.83±0.42) days], and hospitalization time [(11.33±2.70) days] in the observation group were all longer than those in the control group, and the intraoperative blood loss [(271.87±31.56) ml] and the amount of bone cement [(4.55±1.13) ml] were also greater than those in the control group (all P<0.05). The Visual Analogue Scale (VAS) score [(1.18±0.34) points] and the Eastern Cooperative Oncology Group (ECOG) score [(1.07±0.53) points] in the observation group at 6 months after surgery were both lower than those in the control group (both P<0.05). Conclusion　Vertebroplasty and pedicle screw fixation combined with microwave ablation for the treatment of spinal metastases can effectively improve the long-term pain and functional status, which is worthy of clinical promotion.

Key words:

Spinal metastases, Vertebroplasty, Pedicle screw fixation, Microwave ablation

摘要：

目的　探讨椎体成形椎弓钉固定联合微波消融治疗脊柱转移瘤的临床疗效。方法　回顾性分析西安交通大学附属红会医院2022年1月至2023年12月收治的80例脊柱转移瘤患者的临床资料，根据手术方式的不同将患者分为对照组38例与观察组42例。对照组男25例，女13例，年龄（64.78±7.90）岁，病程（5.32±1.60）个月；观察组男28例，女14例，年龄（65.71±9.55）岁，病程（5.51±1.24）个月。对照组采取经皮椎体成形术治疗，观察组采取椎体成形及椎弓钉固定联合微波消融术治疗。统计两组患者一般资料、围手术期指标、随访结果及术后并发症发生情况。采用独立样本t检验、χ²检验进行统计学分析。结果　观察组患者手术时间［（125.69±16.48）min］、下床活动时间［（1.83±0.42）d］和住院时间［（11.33±2.70）d］均长于对照组，术中出血量［（271.87±31.56）ml］、骨水泥量［（4.55±1.13）ml］均大于对照组（均P<0.05）。观察组患者术后6个月视觉模拟评分法（VAS）评分［（1.18±0.34）分］和美国东部肿瘤协作组（ECOG）评分［（1.07±0.53）分］均低于对照组（均P<0.05）。结论　椎体成形及椎弓钉固定联合微波消融术用于治疗脊柱转移瘤可以有效改善患者的长期疼痛和功能状态，值得在临床中推广。

关键词:

脊柱转移瘤, 椎体成形术, 椎弓钉固定, 微波消融

Huang Yunfei, Du Jinpeng, Yang Xiaobin, He Baorong, Li Xiaoju, Zhang Nan.

Clinical efficacy of vertebroplasty and pedicle screw fixation combined with microwave ablation in the treatment of spinal metastases [J]. International Medicine and Health Guidance News, 2025, 31(15): 2539-2543.

黄云飞都金鹏杨小彬贺宝荣李晓菊张楠.

椎体成形椎弓钉固定联合微波消融治疗脊柱转移瘤的临床疗效 [J]. 国际医药卫生导报, 2025, 31(15): 2539-2543.

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