Abstract: Objective　The bone development in adolescents with different degrees of cerebral palsy was investigated by measuring the thickness of cortical bone. Methods　Fifty-one adolescents (29 males and 22 females) aged from 10 to 18 years were randomly selected for the cortical examination of the humerus from Guangzhou Social Welfare Institute from July to December 2020, including 30 cases with normal motor function, 8 cases with mild cerebral palsy, 6 cases with moderate cerebral palsy, and 7 cases with severe cerebral palsy. The radiographs of the right humerus were taken to measure the cortical bone thickness of the humerus. One-way ANOVA was used for overall comparison of the measurement data, and SNK-q test was used for pairwise comparison. Results　The cortical bone thickness of the normal motor function group, the mild cerebral palsy group, the moderate cerebral palsy group, and the severe cerebral palsy group were (4.04±0.82) mm, (4.50±0.82) mm, (3.57±0.99) mm, and (2.97±0.49) mm, respectively, with a statistically significant difference (F=5.067, P=0.004). SNK-q results showed that there was no statistically significant difference in the cortical bone thickness among the normal motor function group, the mild cerebral palsy group, and the moderate cerebral palsy group (P=0.058), and there was no statistically significant difference between the moderate cerebral palsy group and the severe cerebral palsy group (P=0.139). Conclusion　Humeral cortical bone thickness gradually thins as the degree of cerebral paralysis increases to moderate and severe degree.

Key words: Cerebral palsy, Adolescents, Cortical bone thickness

摘要： 目的　通过测量骨皮质厚度，探讨不同瘫痪程度脑瘫青少年的骨发育状况。方法　选取广州市社会福利院2020年7月至12月青少年肱骨骨皮质检查共51例（男29例、女22例，年龄10～18岁），其中运动功能正常组30例、轻度脑瘫组8例、中度脑瘫组6例、重度脑瘫组7例，拍摄右侧肱骨X线片，测量肱骨骨皮质厚度。计量资料整体比较采用单因素方差分析，两两比较采用SNK-q检验。结果　运动功能正常组、轻度脑瘫组、中度脑瘫组、重度脑瘫组骨皮质厚度分别为（4.04±0.82）mm、（4.50±0.82）mm、（3.57±0.99）mm、（2.97±0.49）mm，组间差异有统计学意义（F=5.067，P=0.004）。SNK-q结果表明，运动功能正常组和轻度脑瘫组、中度脑瘫组的骨皮质厚度之间差异无统计学意义（P=0.058），中度脑瘫组与重度脑瘫组的骨皮质厚度之间差异无统计学意义（P=0.139）。结论　肱骨骨皮质厚度随脑瘫程度加重至中重度时会逐渐变薄。

关键词: 脑瘫, 青少年, 骨皮质厚度