International Medicine and Health Guidance News ›› 2022, Vol. 28 ›› Issue (8): 1089-1092.DOI: 10.3760/cma.j.issn.1007-1245.2022.08.012

• Scientific Research • Previous Articles     Next Articles

Two cases of Chlamydia psittaci pneumonia and literature review

Song Xiaobo1, Wu Tingting2, Li Fan1   

  1. 1 Department of Respiratory and Critical Care Medicine, Shanghai Songjiang District Central Hospital, Shanghai 201600, China;

    2 Department of Pharmacy, Shanghai Songjiang District Central Hospital, Shanghai 201600, China

  • Received:2022-01-12 Online:2022-04-15 Published:2022-05-09
  • Contact: Li Fan, Email: lifanking2015@163.com
  • Supported by:
    General Project of Shanghai Municipal Health Commission (201640186)

鹦鹉热衣原体肺炎2例并文献复习

宋晓波1  吴婷婷2  李凡1   

  1. 1上海市松江区中心医院呼吸与危重症医学科,上海 201600

    2上海市松江区中心医院药剂科,上海 201600

  • 通讯作者: 李凡,Email:lifanking2015@163.com
  • 基金资助:
    上海市卫健委面上项目(201640186)

Abstract: Chlamydia psittaci is an atypical pathogen, and is an intracellular parasitic Gram-negative bacterium. Birds are the main hosts and it is zoonotic. This paper reported two cases of pneumonia caused by Chlamydia psittaci infection in Shanghai Songjiang District Central Hospital. One case was complicated with respiratory failure and liver dysfunction, the pathogen was confirmed after next-generation gene sequencing for bronchoscopic alveolar lavage fluid, and the pulmonary inflammation was absorbed and improved after anti-infection. Through case sharing, it can provide references for clinicians in the clinical process of diagnosis and treatment of pneumonia, so that clinicians can accurately evaluate the severity of the disease, identify the pathogen as soon as possible, timely adjust the medication plan, achieve accurate treatment, and get valuable time for the treatment of the disease.

Key words: Chlamydia psittaci, Next-generation gene sequencing, Alveolar lavage fluid

摘要: 鹦鹉热衣原体为不典型致病菌的一种,为胞内寄生的革兰阴性菌,鸟类为最主要宿主,为人畜共患病。本文报道上海市松江区中心医院收治的2例鹦鹉热衣原体感染肺炎,其中1例合并呼吸衰竭、肝功能不全,经支气管镜肺泡灌洗液行二代基因测序后明确病原菌感染,后经抗感染后肺部炎症吸收好转。通过病例分享,为临床医师在诊治肺炎的临床过程中提供参考,准确评估病情的严重程度,尽早明确病原体,及时调整用药方案,达到精准治疗,为疾病的救治赢得宝贵的时间。

关键词: 鹦鹉热衣原体, 二代基因测序, 肺泡灌洗液