International Medicine and Health Guidance News ›› 2022, Vol. 28 ›› Issue (7): 999-1001.DOI: 10.3760/cma.j.issn.1007-1245.2022.07.027

• Case Report • Previous Articles     Next Articles

Cushing's syndrome with hypokalemia and repeated fracture as the first manifestations: report of one case and literature review

Liu Yingxiao, Lin Wenwen, Zhang Yupan   

  1. Department of Endocrinology, Weihai Municipal Hospital, Shandong University, Weihai 264200, China

  • Received:2021-11-19 Online:2022-04-01 Published:2022-05-06
  • Contact: Liu Yingxiao, Email: truelxs@163.com

以低钾血症、反复骨折为首发表现的库欣综合征1例并文献复习

刘英晓  林雯雯  张玉盼   

  1. 山东大学附属威海市立医院内分泌科,威海 264200

  • 通讯作者: 刘英晓,Email:truelxs@163.com

Abstract: Objective To investigate one case of Cushing's syndrome with atypical signs and with hypokalemia and repeated fracture as the first manifestations. Methods The clinical data of a case of Cushing's syndrome with hypokalemia and repeated fractures as the first manifestations in Weihai Municipal Hospital, Shandong University were analyzed, and the literatures were reviewed. Results A 68-year-old female patient was diagnosed as adrenocorticotrophic hormone (ACTH) pituitary tumor in sellar region with hypokalemia and repeated fracture as the first manifestations, and she was improved after surgical treatment. Conclusion Patients with hypokalemia and repeated fracture are prone to missed diagnosis due to atypical clinical signs, and they should be paid attention to in clinical work.

Key words: Hypokalemia, Fracture, Cushing's syndrome, Pituitary adenoma

摘要: 目的 探讨1例以低钾血症、反复骨折为首发表现、体征不典型的库欣综合征。方法 分析山东大学附属威海市立医院1例以低钾血症、反复骨折为首发表现的库欣综合征患者的临床资料,并进行文献复习。结果 该例患者女性,68岁,以低钾血症、反复骨折为首发表现,后诊断为鞍区促肾上腺皮质激素(ACTH)型垂体瘤,经手术治疗好转。结论 有低钾血症、多次骨折病史的患者,因临床体征不典型,易导致漏诊,临床工作中要引起重视。

关键词: 低钾血症, 骨折, 库欣综合征, 垂体瘤