Abstract:

Objective　To explore the consistency of Padua Scale and Khorana Scale in the assessment of venous thromboembolism risk in inpatients with tumors, and to provide references for choosing an appropriate scale for assessing venous thromboembolism risk in inpatients with tumors. Methods　One hundred and thirty-six cancer patients who were admitted to People's Hospital of Guangxi Zhuang Autonomous Region from May to July 2022 were selected for the retrospective analysis, including 76 males and 60 females who were (52.72±15.00) years old. The risk of venous thromboembolism was assessed by both the Padua Scale and the Khorana Scale. The detected rates of thromboembolism risk by the two scales were compared by the χ² test. The consistency of the results of the two scales was analyzed by the Kappa test. Results　The detected rates by the Padua Scale and Khorana Scale on the risk of venous thromboembolism in the patients were 43.38% (59/136) and 41.18% (56/136), respectively, with no statistical difference (P>0.05). The concordance rate of the two scales in the assessment of the risk of venous thromboembolism in the patients was 90.44% (123/136), and the Kappa value was 0.804 (P<0.01), with good concordance. Conclusions　The two scales, Padua and Khorana, have high consistency in the risk assessment of venous thromboembolism in inpatients with tumors. Both can be used as the evaluation criteria for the risk assessment of venous thromboembolism in inpatients with tumors.

Key words:

Malignant tumors, Venous thromboembolism, Risk assessment, Padua Scale, Khorana Scale

摘要：

目的　探讨Padua量表和Khorana量表在肿瘤住院患者静脉血栓栓塞症风险评估中的一致性，为临床肿瘤住院患者静脉血栓栓塞症风险评估选择合适量表提供依据。方法　采用回顾性分析的方法，选取2022年5月至7月在广西壮族自治区人民医院住院的136例恶性肿瘤患者为研究对象，其中男76例、女60例，年龄（52.72±15.00）岁；采用Padua量表和Khorana量表对患者进行静脉血栓栓塞症的风险评估。两种评估工具的血栓风险检出率比较采用χ²检验，二者评估结果的一致性使用Kappa检验分析。结果　Padua量表、Khorana量对肿瘤住院患者存在静脉血栓栓塞症风险的检出率分别为43.38%（59/136）、41.18%（56/136），差异无统计学意义（P>0.05）；二者对肿瘤住院患者静脉血栓栓塞症风险评估的一致性率为90.44%（123/136），Kappa值为0.804（P<0.01），一致性较好。结论　Padua量表、Khorana量表在肿瘤住院患者静脉血栓栓塞症的风险评估中具有较高的一致性，二者均可作为肿瘤住院患者静脉血栓栓塞症风险评估的评价标准。

关键词:

恶性肿瘤, 静脉血栓栓塞症, 风险评估, Padua量表, Khorana量表