One case of acquired cystic kidney disease-associated renal cell carcinoma with ruptured bleeding and urinary leakage

doi:10.3760/cma.j.issn.1007-1245.2024.04.024

Abstract

Abstract:

Acquired cystic kidney disease-associated renal cell carcinoma (ACKD-RCC) is the most common type of renal cell carcinoma that occurs in patients with acquired cystic kidney disease. Due to the unique histopathology of this tumor, it is listed as one of the newly added renal cell carcinoma subtypes in the 2016 edition of the WHO Classification of Renal Tumors. At present, there are few reports on this tumor and most of them are case reports. This paper reports a case of ACKD-RCC, and summarizes its clinicopathological features by referring to relevant literatures, in order to improve the understanding on this rare subtype of renal cell carcinoma.

Key words:

Renal cell carcinoma, , Acquired cystic kidney disease, Rupture, Pathology

摘要：

获得性囊性肾病相关性肾细胞癌（ACKD-RCC）是发生于获得性囊性肾病患者最常见的肾细胞癌类型。鉴于该肿瘤组织病理学独特，2016版世界卫生组织（WHO）肾脏肿瘤分类将其列为新增的肾细胞癌亚型之一。目前，关于该肿瘤的报道较少且多为个案报道，本文报道1例ACKD-RCC，通过查阅相关文献分析总结其临床病理学特征，旨在提高对该少见肾细胞癌亚型的认识。

关键词:

肾细胞癌, 获得性囊性肾病, 破裂, 病理

Tang Yan, Wang Lijuan, Hou Guoqi, Li Yingming.

One case of acquired cystic kidney disease-associated renal cell carcinoma with ruptured bleeding and urinary leakage [J]. International Medicine and Health Guidance News, 2024, 30(4): 634-637.

唐燕王丽娟侯国旗李英明.

获得性囊性肾病相关性肾细胞癌伴破裂出血及尿漏1例 [J]. 国际医药卫生导报, 2024, 30(4): 634-637.

References

[1] Dunnill MS, Millard PR, Oliver D. Acquired cystic disease of the kidnens: a hazard of long-term intermittent maintenance haemodialysis [J]. J Clin Pathol, 1977, 30(9):868-877. DOI: 10.1136/jcp.30.9.868.
[2] Tickoo SK, dePeralta-Venturina MN, Harik LR, et al. Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia [J]. Am J Surg Pathol, 2006, 30(2): 141-153. DOI: 10.1097/01.pas.0000185382. 80844.b1.
[3] Moch H, Humphrey PA, Ulbright TM, et al. WHO classification of tumours of the urinary system and male genital organs [M]. Lyon: IARC Press, 2016.
[4] 饶秋,夏秋媛,周晓军,等. 2016版 WHO 肾脏肿瘤新分类解读[J]. 中华病理学杂志,2016,45(7): 435-441. DOI: 10. 3760/cma.j.issn.0529-5807.2016.07.002.
[5] 施珍,金领微,高依依,等. 血液透析患者获得性肾囊肿的临床回顾分析[J]. 中国中西医结合肾病杂志,2014,15(1):46-47.
[6] Nouh MA, Kuroda N, Yamashita M, et al. Renal cell carcinoma in patients with end-stage renal disease: relationship between histological type and duration of dialysis [J]. BJU Int, 2010, 105(5): 620-627. DOI: 10.1111/j.1464-410X.2009.08817.x.
[7] 杨建勋,付启忠,董圣芳,等. 获得性肾囊性疾病合并肾癌11例临床分析[J]. 中华泌尿外科杂志,2011,32(2):99-102. DOI:10.3760/cma.j.issn.1000-6702.2011.02.008.
[8] Rahbari-Oskoui F, O'Neill WC. Diagnosis and management of acquired cystic kidney disease and renal tumors in ESRD patients[J]. Semin Dial, 2017, 30(4): 373-379. DOI: 10.1111/sdi.12605.
[9] 张伟,徐丽丽,于文娟,等. 获得性囊性肾病相关性肾细胞癌临床病理学观察[J]. 中华病理学杂志,2018,47(5):366-371. DOI:10.3760/cma.j.issn.0529-5807.2018.05.010.
[10] Sule N, Yakupoglu U, Shen SS, et al. Calcium oxalate deposition in renal cell carcinoma associated with acquired cystic kidney disease: a comprehensive study [J]. Am J Surg Pathol, 2005, 29(4): 443-451. DOI: 10.1097/01.pas.0000152131.58492.97.
[11] Ahn S, Kwon GY, Cho YM, et al. Acquired cystic disease-associated renal cell carcinoma: further characterization of the morphologic and immunopathologic features[J]. Med Mol Morphol, 2013, 46(4): 225-232. DOI: 10.1007/s00795-013-0028-x.
[12] Inoue T, Matsuure K, Yoshimoto T, et al. Genomic profiling of renal cell carcinoma in patients with end-stage renal disease[J]. Cancer Sci, 2012, 103(3): 569-576. DOI:10.1111/j.1349-7006.2011.02176.x.
[13] Kuroda N, Tamura M, Hamaguchi N, et al. Acquired cystic disease-associated renal cell carcinoma with sarcomatoid change and rhabdoid features[J]. Ann Diagn Pathol, 2011, 15(6): 462-466. DOI:10.1016/j.anndiagpath.2010.07.008.
[14] Bhatnagar R, Alexiev BA. Renal-cell carcinomas in end-stage kidneys: a clinicopathological study with emphasis on clear-cell papillary renal-cell carcinoma and acquired cystic kidney disease-associated carcinoma [J]. Int J Surg Pathol, 2012, 20(1): 19-28. DOI: 10.1177/1066896911414273.
[15] Przybycin CG, Harper HL, Reynolds JP, et al. Acquired cystic disease-associated renal cell carcinoma (ACD-RCC): a multiinstitutional study of 40 cases with clinical follow-up [J]. Am J Surg Pathol, 2018, 42(9): 1156-1165. DOI: 10.1097/PAS.0000000000001091.
[16] 何冰,张伟,刘莉娜,等. 终末期肾病合并肾细胞癌的临床病理学特征[J]. 中华病理学杂志,2019,48(11):846-850. DOI:10.3760/cma.j.issn.0529?5807.2019.11.003.
[17] 赵媛,陈红,金木兰. 琥珀酸脱氢酶缺陷型肾癌1例并文献复习[J]. 临床与实验病理学杂志,2019,35(12):1472-1474. DOI:10.13315/j.cnki.cjcep.2019.12.021.
[18] Kondo T, Sassa N, Yamada H, et al. Comparable survival outcome between acquired cystic disease associated renal cell carcinoma and clear cell carcinoma in patients with end-stage renal disease: a multi-institutional central pathology study[J]. Pathology, 2021, 53(6): 720-727. DOI: 10.1016/j.pathol.2021.01.014.
[19] 谢红建,宋晓霞,赵跃武,等. 获得性囊性肾病相关性肾细胞癌一例[J].中国临床案例成果数据库,2022, 4(1): E02349-E02349. DOI:10.3760/cma.j.cmcr.2022.e02349.
[20] 陈恕求, 陈明, 张晓文, 等. 长期血透患者获得性囊性肾病合并肾癌8例报告并文献复习[J]. 临床泌尿外科杂志,2012,27(1):33-35. DOI:10.13201/j.issn.1001-1420.2012. 01.014.