Abstract:

Objective　To analyze the effects of respiratory training combined with respiratory tract management on inflammatory indicators and clinical recovery of patients after radical lung cancer surgery. Methods　The clinical data of 80 patients with lung cancer who received radical resection of lung cancer in Lianyungang Hospital of Traditional Chinese Medicine from January 2019 to December 2022 were retrospectively analyzed. The 40 patients who received routine respiratory training and nursing were set as a control group, including 26 males and 14 females who were 59-76 (67.53±2.41) years old. The 40 patients who received respiratory training combined with respiratory management and nursing during the same period were set an observation group, including 27 males and 13 females who were 57-76 (66.97±2.41) years old. The levels of lung function recovery and inflammatory indicators and related complications were compared between the two groups. χ² and t tests were applied. Results　After the nursing, the forced vital capacity (FVC), peak expiratory flow (PEF), and forced expiratory volume in the first second (FEV1) in the observation group were higher than those in the control group [(3.41±0.63) L vs. (3.02±0.51) L, (4.23±0.64) L/min vs. (3.81±0.72) L/min, and (1.71±0.43) L vs. (1.43±0.59) L], with statistical differences (t=3.04, 2.76, and 2.43; all P<0.05). After the nursing, the levels of interleukin-8 (IL-8), IL-10, and tumor necrosis factor-α (TNF-α) in the observation group were lower than those in the control group [(21.98±5.48) μg/L vs. (25.53±5.68) μg/L, (23.08±6.05) μg/L vs. (27.54±5.56) μg/L, and (23.97±6.45) pg/L vs. (28.53±6.25) pg/L], with statistical differences (t=2.85, 3.43, and 3.21; all P<0.05). The incidences of complications after the surgery in the observation group was lower than that in the control group [5.00% (2/40) vs. 20.00% (8/40)], with a statistical difference (χ²=4.11, P<0.05). Conclusion　Respiratory training combined with respiratory tract management for patients after radical lung cancer surgery can effectively improve their recovery of lung function and reduce the levels of inflammatory indicators and the occurrence of related complications.

Key words:

Respiratory training, Respiratory tract, Lung cancer, Inflammatory indicators, Recovery effect

摘要：

目的　分析呼吸训练联合呼吸道管理对肺癌根治术后患者炎症指标以及临床恢复效果的影响。方法　回顾性分析在连云港市中医院2019年1月至2022年12月期间接受肺癌根治术治疗的80例肺癌患者临床资料，其中接受常规呼吸训练护理的40例患者作为对照组，同期接受呼吸训练联合呼吸道管理护理的40例患者作为观察组。对照组男26例、女14例，年龄59～76（67.53±2.41）岁；观察组男27例、女13例，年龄57～76（66.97±2.41）岁。对比两组患者肺功能恢复水平、炎症指标水平以及相关并发症发生情况。统计学方法采用χ²检验、t检验。结果　护理后，观察组患者用力肺活量（FVC）、呼气流量峰值（PEF）、第一秒用力呼气量（FEV1）水平均高于对照组［（3.41±0.63）L比（3.02±0.51）L、（4.23±0.64）L/min比（3.81±0.72）L/min、（1.71±0.43）L比（1.43±0.59）L］，差异均有统计学意义（t=3.04、2.76、2.43，均P<0.05）；护理后，观察组患者白细胞介素-8（IL-8）、白细胞介素-10（IL-10）、肿瘤坏死因子-α（TNF-α）均低于对照组［（21.98±5.48）μg/L比（25.53±5.68）μg/L、（23.08±6.05）μg/L比（27.54±5.56）μg/L、（23.97±6.45）pg/L比（28.53±6.25）pg/L］，差异均有统计学意义（t=2.85、3.43、3.21，均P<0.05）；观察组患者肺癌根治术后并发症发生率低于对照组［5.00%（2/40）比20.00%（8/40）］，差异有统计学意义（χ²=4.11，P<0.05）。结论　对肺癌根治术患者应用常规呼吸训练联合呼吸道管理，可有效提高患者肺功能恢复水平，降低炎症指标表达水平以及相关并发症的发生。

关键词:

呼吸训练, 呼吸道, 肺癌, 炎症指标, 恢复效果