Abstract:

This article reports an elderly diabetic patients at Weihai Central Hospital, Qingdao University. The patient had a fever after taking pantoprazole sodium for injection after stent placement in the left subclavian artery. After having a fever, the patient took anti-infection and anti-fever treatment, but had no ideal effect. The lung CT showed no pulmonary infection and the 2 cultures were negative, so the pharmacist doubted that it was drug fever, and recommended the patient stopped the suspicious drugs, and the patient's body temperature returned to normal. The case analysis showed that the patient could have a fever after intravenous infusion of pantoprazole sodium for injection. Therefore, the clinical occurrence of unexplained fever should be considered the possibility of drug fever.

Key words:

Drug fever, Pantoprazole, Adverse drug reactions

摘要：

本文报道1例青岛大学附属威海市中心医院老年糖尿病患者，该患者在接受左侧锁骨下动脉支架置入术后使用注射用泮托拉唑钠后出现高热。患者发热后，临床给予抗感染治疗及对症退热治疗，效果不理想。肺部CT不支持肺部感染，2次培养均阴性，药师怀疑药物热，建议停用可疑药物，之后患者体温趋于正常。通过对病例进行分析，患者发热极有可能是由静脉滴注注射用泮托拉唑钠导致的药物热，临床中出现不明原因发热需要考虑到药物热的可能性。

关键词:

药物热, 泮托拉唑, 不良反应