Abstract: Objective　To explore the effect of evidence-based nursing care for preschool children with type 1 diabetes taking long-term insulin pump therapy. Methods　From June 2018 to March 2021, 136 preschool children with type 1 diabetes treated at Children's Hospital of Zhengzhou University were selected as experimental subjects. They were divided into an observation group and a control group by the isometric sampling method, with 68 cases in each group. The observation group had 38 boys and 30 girls who were (4.86±1.13) years old, and took evidence-based nursing care. The control group had 36 boys and 32 girls who were (4.75±1.24) years old, and took routine care. The general data, such as blood glucose, body weight, age, gender, and height, in both groups were investigated. The blood glucose levels, Caregiver Burden Scale (CBI) scores, negative emotions, various compliance behaviors, and negative events of insulin pump were compared between the two groups after the nursing care. The measurement data of normal distribution were expressed as (x±s), and compared between the two groups by LSD-t test. The enumeration data were expressed as cases (%), and compared between the two groups by χ² test. Results　Three months after the nursing care, the 2-hour postprandial blood glucose, fast blood glucose, hemoglobin A1C, and scores of Self-rating Depression Scale and Self-rating Anxiety Scale were (6.58±1.39) mmol/L, (5.18±0.11) mmol/L, (6.32±0.27)%, (43.39±2.21), and (42.16±3.37) in the observation group, which were lower than those in the control group (all P<0.05). The scores of CBI 1 and 3 months after the nursing care were (47.36±3.12) and (42.86±3.32) in the observation group, which were lower than those in the control group (both P<0.05). More patients correctly changed the sites, checked the injection sites every day, monitored blood glucose every day, carried backup drugs and tools with them, and safely kept the drugs and tools in the observation group [97.06% (66/68), 98.53% (67/68), 100.00% (68/68), 92.65% (63/68), and 97.06% (66/68)] than in the control group (all P<0.05). The incidence of the negative insulin pump events was 4.41% (3/68) in the observation group, which was lower than that in the control group (P<0.05). Conclusion　Evidence-based nursing care for preschool children with type 1 diabetes can standardize the long-term use of insulin pumps and reduce the incidence of accidents.

Key words: Evidence-based nursing care, Diabetes, Insulin pumps

摘要： 目的　探讨循证护理应用于规范携带胰岛素泵学龄前1型糖尿病患儿的效果。方法　在2018年6月至2021年3月期间选择郑州大学附属儿童医院136例学龄前1型糖尿病患儿为试验对象，根据等距抽样法分为两组：观察组68例［男性38例，女性30例，年龄（4.86±1.13）岁］采用循证护理，对照组68例［男性36例，女性32例，年龄（4.75±1.24）岁］采用常规护理。调查两组患儿血糖、体质量、年龄、性别、身高等一般资料，并比较两组护理后血糖水平、照顾者负担量表（CBI）评分、负面情绪以及各项遵医行为，统计各类胰岛素泵负性事件。符合正态分布的计量资料用（x±s）表示，两两比较用LSD-t检验；计数资料用（%）表示，两组间比较采用χ²检验。结果　观察组护理后3个月餐后2 h血糖（6.58±1.39）mmol/L、空腹血糖（5.18±0.11）mmol/L、糖化血红蛋白（6.32±0.27）%、抑郁自评量表评分（43.39±2.21）分、焦虑自评量表评分（42.16±3.37）分，均低于对照组（均P<0.05）。观察组护理后1、3个月CBI评分（47.36±3.12）分、（42.86±3.32）分，均低于对照组（均P<0.05）。观察组正确更换部位97.06%（66/68）、每日检查注射部位98.53%（67/68）、每日血糖监测100.00%（68/68）、随身携带备用药品或工具92.65%（63/68）、妥善保存97.06%（66/68），均高于对照组（均P<0.05）；观察组胰岛素泵负性事件4.41%（3/68），低于对照组（P<0.05）。结论　对学龄前1型糖尿病患儿秉持循证护理，能够规范长期携带胰岛素泵的使用，降低意外事件发生率。

关键词: 循证护理, 糖尿病, 胰岛素泵