Abstract:

Objective　To investigate the effect of percutaneous vertebroplasty (PVP) in the treatment of senile osteoporotic vertebral fractures. Methods　A total of 112 senile patients with osteoporotic vertebral fractures admitted to Huai'an First Hospital, Nanjing Medical University from March 2017 to February 2019 were selected and divided into a study group and a conventional group according to the surgical methods, with 56 cases in each group. There were 36 males and 20 females in the study group; they were 60-81 (69.36±7.89) years old. There were 35 males and 21 females in the conventional group; they were 61-83 (69.89±7.93) years old. The study group were treated by PVP, and the conventional group by percutaneous screw internal fixation. The vertebral compression rates, vertebral height recovery (operation time and amount of bone cement injection), and incidences of adverse reactions of the two groups were compared. t and χ² tests were applied. Results　After the surgery, the vertebral compression rate and vertebral height recovery in the study group were statistically higher than those in the conventional group (t=5.20 and 5.46; both P<0.05). The operation time in the study group was shorter than that in the conventional group (t=5.19, P<0.05). The amount of bone cement injection in the study group was less than that in the conventional group (t=16.248, P<0.05). The incidence of adverse reactions in the study group was lower than that in the conventional group [3.57% (2/56) vs. 14.29% (8/56)], with a statistical difference (χ²=3.953, P<0.05). Conclusions　PVP for elderly patients with osteoporotic vertebral fractures can effectively restore the vertebral height, improve the vertebral compression rate, and has high safety.

Key words:

Percutaneous vertebroplasty, Senile osteoporotic vertebral fractures, Vertebral compression rat, Vertebral height recovery

摘要：

目的　探究经皮椎体成形术（PVP）治疗老年性骨质疏松性椎体骨折的疗效。方法　选取2017年3月至2019年2月于南京医科大学附属淮安第一医院收治的112例老年性骨质疏松性椎体骨折患者，按照手术方式的不同将其分为研究组和常规组。研究组56例，男36例、女20例，年龄60～81（69.36±7.89）岁，实施PVP；常规组56例，男35例、女21例，年龄61～83（69.89±7.93）岁，实施经皮螺钉内固定手术，比较两组患者椎体压缩率、椎体高度恢复情况（手术时间、骨水泥注射量）及不良反应发生率。统计学方法采用t检验、χ²检验。结果　术后研究组椎体压缩率、椎体高度恢复情况均高于常规组，差异均有统计学意义（t=5.20、5.46，均P<0.05）。研究组患者手术时间短于常规组，骨水泥注射量少于常规组，差异均有统计学意义（t=5.19、16.25，均P<0.05）。研究组不良反应发生率低于常规组［3.57%（2/56）比14.29%（8/56）］，差异有统计学意义（χ²=3.953，P<0.05）。结论　对于老年性骨质疏松性椎体骨折患者，PVP能够有效恢复椎体高度，提高椎体压缩率，且安全性较高。

关键词:

经皮椎体成形术, 老年性骨质疏松症, 椎体压缩率, 椎体高度恢复