国际医药卫生导报 ›› 2025, Vol. 31 ›› Issue (12): 1997-2001.DOI: 10.3760/cma.j.cn441417-20250430-12014

• 论著 • 上一篇    下一篇

经阴道彩色多普勒超声在子宫腺肌瘤和子宫肌瘤中的诊断价值

李静 王小华 于翠玲 于晓勇   

  1. 珠海市中西医结合医院超声医学科,珠海 519000

  • 收稿日期:2025-04-30 出版日期:2025-06-15 发布日期:2025-06-15
  • 通讯作者: 于晓勇,Email:15916257117@139.com
  • 基金资助:

    广东省中医药局科研项目(20231311);珠海市社会发展领域科技计划(2320004000338)

Value of transvaginal color Doppler ultrasound in diagnosis of uterine adenomyosis and uterine fibroids 

Li Jing, Wang Xiaohua, Yu Cuiling, Yu Xiaoyong   

  1. Department of Ultrasound Medicine, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Zhuhai 519000, China

  • Received:2025-04-30 Online:2025-06-15 Published:2025-06-15
  • Contact: Yu Xiaoyong, Email: 15916257117@139.com
  • Supported by:

    Scientific Research Project of Guangdong Bureau of Traditional Chinese Medicine (20231311); Plan of Science and Technology of Social Development Field in Zhuhai (2320004000338)

摘要:

目的 探讨经阴道彩色多普勒超声(TVCD)在子宫腺肌瘤和子宫肌瘤诊断中的应用价值。方法 采用回顾性研究设计,选取2023年3月至2025年3月在珠海市中西医结合医院妇科就诊的102例疑似子宫腺肌瘤或子宫肌瘤患者为研究对象,年龄(42.35±6.72)岁。均接受TVCD检查,记录声像图特征及血流信号特点,并与手术病理结果对照。采用tχ2检验或Fisher确切概率法进行统计比较,计算TVCD诊断两种疾病的灵敏度、特异度、准确度、阳性预测值和阴性预测值。结果 102例患者中,经手术病理确诊为子宫腺肌瘤45例,子宫肌瘤51例,两者并存6例。6例两者并存患者不纳入敏感性、特异性等分析。TVCD诊断子宫腺肌瘤的灵敏度为93.33%(42/45)、特异度为92.16%(47/51)、准确度为92.71%(89/96)、阳性预测值为91.30%(42/46)、阴性预测值为94.00%(47/50)。TVCD诊断子宫肌瘤的灵敏度为94.12%(48/51)、特异度为91.11%(41/45)、准确度为92.71%(89/96)、阳性预测值为92.31%(48/52)、阴性预测值为93.18%(41/44)。在TVCD中,子宫腺肌瘤主要表现为子宫增大、肌层回声不均、囊性区域及子宫后壁增厚等;子宫肌瘤则主要表现为类圆形低回声或等回声肿块,边界清晰,后方回声增强或衰减。子宫腺肌瘤的血流呈弥散分布,阻力指数(RI)为(0.52±0.07);子宫肌瘤血流多呈周边环绕状,RI为(0.64±0.06);两者RI比较,差异有统计学意义(P<0.05)。结论 TVCD对子宫腺肌瘤、子宫肌瘤具有较高的诊断价值,其特征性表现及血流特点可为临床鉴别诊断提供重要依据。

关键词: 子宫腺肌瘤, 子宫肌瘤, 经阴道彩色多普勒超声, 诊断价值, 血流特点

Abstract:

Objective To explore the clinical value of transvaginal color Doppler ultrasound (TVCD) in the diagnosis of uterine adenomyosis and uterine fibroids. Methods A retrospective study was conducted on 102 patients with suspected uterine adenomyosis or uterine fibroids who visited Department of Gynecology, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine from March 2023 to March 2025. They were (42.35±6.72) years old. All the patients underwent TVCD examination, and their sonographic features and blood flow signal characteristics were recorded and compared with the surgical pathological results. t and χ2 tests and Fisher's precision probability test were used for the statistical comparisons. The sensitivities, specificities, accuracies, positive predictive values, and negative predictive values of TVCD for diagnosing these two diseases were calculated. Results Among the 102 patients, 45 had uterine adenomyosis, 51 had uterine fibroids, and 6 had both conditions, confirmed by surgical pathology. Six patients with both coexisting conditions were not included in the analyses of sensitivity, specificity, etc. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of TVCD for diagnosing uterine adenomyosis were 93.33% (42/45), 92.16% (47/51), 92.71% (89/96), 91.30% (42/46), and 94.00% (47/50), respectively. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of TVCD for diagnosing uterine fibroids were 94.12% (48/51), 91.11% (41/45), 92.71% (89/96), 92.31% (48/52), and 93.18% (41/44), respectively. Uterine adenomyosis on TVCD mainly manifested as an enlarged uterus, heterogeneous myometrial echoes, cystic areas, and thickened posterior wall; uterine fibroids mainly presented as round hypoechoic or isoechoic masses with clear boundaries and posterior echo enhancement or attenuation. The blood flow of uterine adenomyosis showed a diffuse distribution, with a resistance index (RI) of 0.52±0.07; uterine fibroids showed predominantly peripheral blood flow, with an RI of 0.64±0.06; there was a statistical difference in RI between them (P<0.05). Conclusions TVCD has high diagnostic value for uterine adenomyosis and uterine fibroids. Its characteristic manifestations and blood flow patterns provide important evidences for clinical differential diagnosis.

Key words: Uterine adenomyosis,  , Uterine fibroids,  , Transvaginal color Doppler ultrasound,  , Diagnostic value,  , Blood flow characteristics