杯状核细胞AML-M1伴NPM1、GATA2突变1例

doi:10.3760/cma.j.cn441417-20240914-06033

国际医药卫生导报 ›› 2025, Vol. 31 ›› Issue (6): 1047-1049.DOI: 10.3760/cma.j.cn441417-20240914-06033

杯状核细胞AML-M1伴NPM1、GATA2突变1例

徐道晶¹ 朱海燕¹ 于洁²

¹山东大学附属威海市立医院检验科，威海 264200；²山东大学附属威海市立医院血液科，威海 264211

收稿日期:2024-11-20 出版日期:2025-03-15 发布日期:2025-03-17
通讯作者: 于洁，Email：yujiejessica@126.com
基金资助:
山东省医药卫生科技发展计划（202103040787）

Cup-like AML-M1 with NPM1 and GATA2 mutations in one patient

Xu Daojing¹, Zhu Haiyan¹, Yu Jie²

¹Clinical Laboratory, Weihai Municipal Hospital, Shandong University, Weihai 264200, China; ²Department of Hematology, Weihai Municipal Hospital, Shandong University, Weihai 264211, China

Received:2024-11-20 Online:2025-03-15 Published:2025-03-17
Contact: Yu Jie, Email: yujiejessica@126.com
Supported by:
Plan for Development of Medicine and Health Science and Technology in Shandong (202103040787)

摘要/Abstract

摘要：

急性白血病（acute leukemia，AL）按照系列归属分为急性髓细胞白血病（acute myeloid leukemia，AML）和急性淋巴细胞白血病（acute lymphocytic leukemia，ALL）两大类。未分化型AML（AML-M1）是AML的一种亚型。AML-M1患者骨髓中没有分化的原始粒细胞>90%，化疗缓解率低。

关键词:

急性髓细胞白血病, NPM1突变, GATA2突变, 杯状细胞

Abstract:

Acute leukemia (AL) is classified into acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL). AML undifferentiated (AML-M1) is a subtype of AML. The undifferentiated myeloblasts in the marrow are more than 90% in AML-M1 patients, and the response rate of chemotherapy is low.

Key words:

Acute myeloid leukemia, NPM1 mutation, GATA2 mutation, Cup-like nucleicell

徐道晶朱海燕于洁.

杯状核细胞AML-M1伴NPM1、GATA2突变1例 [J]. 国际医药卫生导报, 2025, 31(6): 1047-1049.

Xu Daojing, Zhu Haiyan, Yu Jie.

Cup-like AML-M1 with NPM1 and GATA2 mutations in one patient [J]. International Medicine and Health Guidance News, 2025, 31(6): 1047-1049.

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杯状核细胞AML-M1伴NPM1、GATA2突变1例

Cup-like AML-M1 with NPM1 and GATA2 mutations in one patient

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